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CANCER RESEARCH (2004)
The EF-hand Ca2+-binding protein p22 plays a role in microtubule and endoplasmic reticulum organization and dynamics with distinct Ca2+-binding requirements
J Andrade et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
β-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
AY Abramov et al.
JOURNAL OF NEUROSCIENCE (2004)
Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1
A Varadi et al.
JOURNAL OF CELL SCIENCE (2004)
Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1
PP Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural basis of mitochondrial tethering by mitofusin complexes
T Koshiba et al.
SCIENCE (2004)
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
KM Vattem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity
N Ishihara et al.
JOURNAL OF CELL SCIENCE (2004)
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
SJ Marciniak et al.
GENES & DEVELOPMENT (2004)
Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
R Sugioka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Calcium and mitochondria: mechanisms and functions of a troubled relationship
K Bianchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Variation of mitochondrial size during the cell cycle: A multiparameter flow cytometric and microscopic study
PK Kennady et al.
CYTOMETRY PART A (2004)
Amyloid β-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis
U Keil et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Translocation of bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis
N Morishima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mitochondria-specific function of the dynamin family protein DLP1 is mediated by its C-terminal domains
KR Pitts et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mitochondrial fission proteins regulate programmed cell death in yeast
Y Fannjiang et al.
GENES & DEVELOPMENT (2004)
OPA1 requires mitofusin 1 to promote mitochondrial fusion
S Cipolat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
YJ Lee et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Inositol 1,4,5-trisphosphatereceptors as signal integrators
RL Patterson et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
PD Lu et al.
JOURNAL OF CELL BIOLOGY (2004)
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6
JS Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis
G Szabadkai et al.
MOLECULAR CELL (2004)
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death
J Hitomi et al.
JOURNAL OF CELL BIOLOGY (2004)
A trip to the ER: coping with stress
DT Rutkowski et al.
TRENDS IN CELL BIOLOGY (2004)
Cell degeneration induced by amyloid-beta peptides - Implications for Alzheimer's disease
C Pereira et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2004)
Global prevalence of diabetes - Estimates for the year 2000 and projections for 2030
S Wild et al.
DIABETES CARE (2004)
The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle
M Suzuki et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Regulation of endoplasmic reticulum Ca2+ dynamics by proapoptotic BCL-2 family members
SA Oakes et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax
XF Cao et al.
BLOOD (2003)
hFis1, a novel component of the mammalian mitochondrial fission machinery
DI James et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Two mitofusin proteins, mammalian homologues of FZO, with distinct functions are both required for mitochondrial fusion
Y Eura et al.
JOURNAL OF BIOCHEMISTRY (2003)
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
Y Yoon et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
σ-1 receptors (σ1 binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum:: Roles in endoplasmic reticulum lipid compartmentalization and export
T Hayashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells
A Santel et al.
JOURNAL OF CELL SCIENCE (2003)
Activation signal of nuclear factor-κB in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2
M Kaneko et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2003)
Spatial and temporal dynamics of budding yeast mitochondria lacking the division component Fis1p
S Jakobs et al.
JOURNAL OF CELL SCIENCE (2003)
The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lα
B Gess et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
BAX and BAK regulation of endoplasmic reticulum Ca2+:: A control point for apoptosis
L Scorrano et al.
SCIENCE (2003)
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
DG Breckenridge et al.
JOURNAL OF CELL BIOLOGY (2003)
Dynamin-like protein 1 is involved in peroxisomal fission
A Koch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
K Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1α to the endoplasmic reticulum and promotes dephosphorylation of the α subunit of eukaryotic translation initiation factor 2
MH Brush et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
A time-dependent phase shift in the mammalian unfolded protein response
H Yoshida et al.
DEVELOPMENTAL CELL (2003)
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
HC Chen et al.
JOURNAL OF CELL BIOLOGY (2003)
Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity
KC Suen et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
M Karbowski et al.
JOURNAL OF CELL BIOLOGY (2002)
Endoplasmic reticulum stress and the development of diabetes - A review
HP Harding et al.
DIABETES (2002)
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria
E Rapizzi et al.
JOURNAL OF CELL BIOLOGY (2002)
The endoplasmic reticulum: a multifunctional signaling organelle
MJ Berridge
CELL CALCIUM (2002)
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations
O Milhavet et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
FM LaFerla
NATURE REVIEWS NEUROSCIENCE (2002)
Amyloid β peptide induces cytochrome c release from isolated mitochondria
HS Kim et al.
NEUROREPORT (2002)
An endoplasmic reticulum stress-specific caspase cascade in apoptosis -: Cytochrome c-independent activation of caspase-9 by caspase-12
N Morishima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response
T Okada et al.
BIOCHEMICAL JOURNAL (2002)
Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease
O Hori et al.
JOURNAL OF CELL BIOLOGY (2002)
Coupling endoplasmic reticulum stress to the cell death program - An Apaf-1-independent intrinsic pathway
RV Rao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
H Nishitoh et al.
GENES & DEVELOPMENT (2002)
Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice
A Matsuzawa et al.
ANTIOXIDANTS & REDOX SIGNALING (2002)
BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria
M Germain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines
DH Margineantu et al.
MITOCHONDRION (2002)
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
T Gotoh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mitochondria are morphologically and functionally heterogeneous within cells
TJ Collins et al.
EMBO JOURNAL (2002)
Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores
LK Nutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78
RV Rao et al.
FEBS LETTERS (2002)
IREI-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
K Lee et al.
GENES & DEVELOPMENT (2002)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
H Yoshida et al.
CELL (2001)
Mutation spectrum and splicing variants in the OPA1 gene
C Delettre et al.
HUMAN GENETICS (2001)
Dissecting glycoprotein quality control in the secretory pathway
CM Cabral et al.
TRENDS IN BIOCHEMICAL SCIENCES (2001)
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
S Frank et al.
DEVELOPMENTAL CELL (2001)
Coupling endoplasmic reticulum stress to the cell death program - Mechanism of caspase activation
RV Rao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mammalian dynamin-like protein DLP1 tubulates membranes
Y Yoon et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
ER quality control: towards an understanding at the molecular level
L Ellgaard et al.
CURRENT OPINION IN CELL BIOLOGY (2001)
Endonuclease G is an apoptotic DNase when released from mitochondria
LY Li et al.
NATURE (2001)
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
MC Wei et al.
SCIENCE (2001)
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
T Yoneda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state
KD McCullough et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
J Ye et al.
MOLECULAR CELL (2000)
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
T Lindsten et al.
MOLECULAR CELL (2000)
Phosphatidylserine synthase-1 and-2 are localized to mitochondria-associated membranes
SJ Stone et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Signal transduction by the JNK group of MAP kinases
RJ Davis
CELL (2000)
Cross-talk between two cysteine protease families: Activation of caspase-12 by calpain in apoptosis
T Nakagawa et al.
JOURNAL OF CELL BIOLOGY (2000)
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
CY Du et al.
CELL (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)
Mitochondrial DNA depletion causes morphological changes in the mitochondrial reticulum of cultured human cells
RW Gilkerson et al.
FEBS LETTERS (2000)
Mitochondria-targeted GFP highlights the heterogeneity of mitochondrial shape, size and movement within living plant cells
DC Logan et al.
JOURNAL OF EXPERIMENTAL BOTANY (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
T Nakagawa et al.
NATURE (2000)
Intraneuronal A beta 42 accumulation in human brain
GK Gouras et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Caspase-resistant BAP31 inhibits Fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria
M Nguyen et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
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