期刊
JOURNAL OF CELLULAR BIOCHEMISTRY
卷 104, 期 5, 页码 1541-1552出版社
WILEY-LISS
DOI: 10.1002/jcb.21746
关键词
lysine deacetylase; Rpd3; Hda1; Sir2; SIRT1; MEF2; HDAC inhibitor
Histone deacetylase (HDAC) activity was first discovered about 40 years ago, but it Was not until the molecular identifications of the first HDACs in 1996 that this family of enzymes gained prominence. In addition to histones, HDACs reverse lysine acetylation of various non-histone proteins located in the nucleus and the cytoplasm. Here, we examine the nuclear roles of these enzymes, with a specific focus on their active crosstalk with different chromatin regulators.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据