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注意:仅列出部分参考文献,下载原文获取全部文献信息。SecYEG activates GTPases to drive the completion of cotranslational protein targeting
David Akopian et al.
JOURNAL OF CELL BIOLOGY (2013)
Competitive Binding of the SecA ATPase and Ribosomes to the SecYEG Translocon
Zht Cheng Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Activated GTPase movement on an RNA scaffold drives co-translational protein targeting
Kuang Shen et al.
NATURE (2012)
Dynamic switch of the signal recognition particle from scanning to targeting
Wolf Holtkamp et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
A single copy of SecYEG is sufficient for preprotein translocation
Alexej Kedrov et al.
EMBO JOURNAL (2011)
Lipids Trigger a Conformational Switch That Regulates Signal Recognition Particle (SRP)-mediated Protein Targeting
Goran Stjepanovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Site-Specific Fluorescent Labeling of Nascent Proteins on the Translating Ribosome
Ishu Saraogi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Signal sequence-independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle
David Braig et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Preserving the membrane barrier for small molecules during bacterial protein translocation
Eunyong Park et al.
NATURE (2011)
Structural basis of signal-sequence recognition by the signal recognition particle
Tobias Hainzl et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Direct visualization reveals dynamics of a transient intermediate during protein assembly
Xin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting
Kuang Shen et al.
RNA (2011)
The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
Sandro F. Ataide et al.
SCIENCE (2011)
Molecular Mechanism of Co-translational Protein Targeting by the Signal Recognition Particle
Ishu Saraogi et al.
TRAFFIC (2011)
Defining the Specificity of Cotranslationally Acting Chaperones by Systematic Analysis of mRNAs Associated with Ribosome-Nascent Chain Complexes
Marta del Alamo et al.
PLOS BIOLOGY (2011)
Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting
Vinh Q. Lam et al.
JOURNAL OF CELL BIOLOGY (2010)
Recognition of a signal peptide by the signal recognition particle
Claudia Y. Janda et al.
NATURE (2010)
Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting
Kuang Shen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Sequential Checkpoints Govern Substrate Selection During Cotranslational Protein Targeting
Xin Zhang et al.
SCIENCE (2010)
Signal Recognition Particle (SRP) and SRP Receptor: A New Paradigm for Multistate Regulatory GTPases
Shu-ou Shan et al.
BIOCHEMISTRY (2009)
The Lateral Gate of SecYEG Opens during Protein Translocation
David J. F. du Plessis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Two Cooperating Helices Constitute the Lipid-binding Domain of the Bacterial SRP Receptor
David Braig et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
It takes two to tango: regulation of G proteins by dimerization
Raphael Gasper et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Delivering proteins for export from the cytosol
Benedict C. S. Cross et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins
Guenter Kramer et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Multiple conformational switches in a GTPase complex control co-translational protein targeting
Xin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Demonstration of a multistep mechanism for assembly of the SRP.SRP receptor complex: Implications for the catalytic role of SRP RNA
Xin Zhang et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Signal sequence-independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel
Thomas Bornemann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Ribosome binding of a single copy of the SecY complex:: Implications for protein translocation
Jean-Francois Menetret et al.
MOLECULAR CELL (2007)
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes
Tom A. Rapoport
NATURE (2007)
Following the signal sequence from ribosomal tunnel exit to signal recognition particle
Mario Halic et al.
NATURE (2006)
Structure of the E-coli signal recognition particle bound to a translating ribosome
Christiane Schaffitzel et al.
NATURE (2006)
Signal recognition particle receptor exposes the ribosomal translocon binding site
M Halic et al.
SCIENCE (2006)
Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation
ZL Cheng et al.
JOURNAL OF CELL BIOLOGY (2005)
Heterodimeric GTPase core of the SRP targeting complex
PJ Focia et al.
SCIENCE (2004)
Substrate twinning activates the signal recognition particle and its receptor
PF Egea et al.
NATURE (2004)
X-ray structure of a protein-conducting channel
B van den Berg et al.
NATURE (2004)
Mechanism of association and reciprocal activation of two GTPases
SO Shan et al.
PLOS BIOLOGY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome
RS Ullers et al.
JOURNAL OF CELL BIOLOGY (2003)
Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens
JJ Flanagan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The signal recognition particle binds to protein L23 at the peptide exit of the Escherichia coli ribosome
SQ Gu et al.
RNA (2003)
Distinct modes of signal recognition particle interaction with the ribosome
MR Pool et al.
SCIENCE (2002)
Role of SRP RNA in the GTPase cycles of ffh and FtsY
P Peluso et al.
BIOCHEMISTRY (2001)
Role of Sec61α in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel
WQ Song et al.
CELL (2000)