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EMBO JOURNAL (2009)
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Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments
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Kinetochore stretching inactivates the spindle assembly checkpoint
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Regulation of Kinetochore Recruitment of Two Essential Mitotic Spindle Checkpoint Proteins by Mps1 Phosphorylation
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Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization
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Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied
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Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly
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JOURNAL OF CELL BIOLOGY (2008)
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
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JOURNAL OF CELL BIOLOGY (2008)
Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells
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Phosphorylation relieves autoinhibition of the kinetochore motor Cenp-E
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MOLECULAR CELL (2008)
Chromosomal Instability by Inefficient Mps1 Auto-Activation Due to a Weakened Mitotic Checkpoint and Lagging Chromosomes
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PLOS ONE (2008)
Aurora B kinase-dependent recruitment of hZW10 and hROD to tensionless kinetochores
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CURRENT BIOLOGY (2007)
Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint
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Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
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The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule-kinetochore interactions
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Mps1 activation loop autophosphorylation enhances kinase activity
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
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Reversine increases the plasticity of lineage-committed mammalian cells
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Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1
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CURRENT BIOLOGY (2007)
Does aneuploidy cause cancer?
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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
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CELL (2006)
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
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CELL (2006)
Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors
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Aurora B is enriched at merotelic attachment sites, where it regulates MCAK
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CURRENT BIOLOGY (2006)
Mps1 phosphorylation by MAP kinase is required for kinetochore localization of spindle-checkpoint proteins
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CURRENT BIOLOGY (2006)
Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase
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CURRENT BIOLOGY (2006)
Phosphate-binding tag, a new tool to visualize phosphorylated proteins
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EMBO REPORTS (2005)
A small-molecule inhibitor of mpsl blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes
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Chemical genetics reveals a role for Mps1 kinase in kinetochore attachment during mitosis
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NATURE CELL BIOLOGY (2004)
Aurora B regulates MCAK at the mitotic centromere
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Dedifferentiation of lineage-committed cells by a small molecule
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Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1
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CHROMOSOMA (2004)
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Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
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JOURNAL OF CELL BIOLOGY (2003)
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint
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S-pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response
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CELL (2003)
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis
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CURRENT BIOLOGY (2002)
Evidence that the Ipl1-Sli15 (Aurora knase-INCENP) complex by altering promotes chromosome bi-orientation kinetochore-spindle pole connections
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CELL (2002)
The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the, spindle checkpoint
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Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for spindle checkpoint
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