4.0 Article

Recent Development in Carbohydrate Based Anticancer Vaccines

期刊

JOURNAL OF CARBOHYDRATE CHEMISTRY
卷 31, 期 1-3, 页码 143-186

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/07328303.2012.659364

关键词

Carbohydrate antigen; Glyco-conjugates; Anti-cancer vaccine; Immune responses

资金

  1. National Cancer Institute [R01CA149451-01A1]
  2. NATIONAL CANCER INSTITUTE [R01CA149451] Funding Source: NIH RePORTER

向作者/读者索取更多资源

The development of carbohydrate-based anticancer vaccines is of high current interest. Herein, the latest development in this exciting field is reviewed. After a general introduction about tumor-associated carbohydrate antigens and immune responses, the review focuses on the various strategies that have been developed to enhance the immunogenicity of these antigens. The results from animal studies and clinical trials are presented.

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