期刊
JOURNAL OF CARBOHYDRATE CHEMISTRY
卷 31, 期 1-3, 页码 143-186出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/07328303.2012.659364
关键词
Carbohydrate antigen; Glyco-conjugates; Anti-cancer vaccine; Immune responses
资金
- National Cancer Institute [R01CA149451-01A1]
- NATIONAL CANCER INSTITUTE [R01CA149451] Funding Source: NIH RePORTER
The development of carbohydrate-based anticancer vaccines is of high current interest. Herein, the latest development in this exciting field is reviewed. After a general introduction about tumor-associated carbohydrate antigens and immune responses, the review focuses on the various strategies that have been developed to enhance the immunogenicity of these antigens. The results from animal studies and clinical trials are presented.
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