期刊
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
卷 113, 期 1, 页码 73-75出版社
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/j.jbiosc.2011.09.002
关键词
Candida utilis; Xylose; L-lactic acid; Xylose reductase; Xylitol dehydrogenase
Efficient L-lactic acid production from xylose was achieved using a pyruvate decarboxylase-deficient Candida utilis strain expressing an L-lactate dehydrogenase, an NADH-preferring mutated xylose reductase (XR), a xylitol dehydrogenase and a xylulokinase. The recombinant strain showed 53% increased L-lactic acid production compared with the reference strain expressing native XR (NADPH-preferring). (C) 2011, The Society for Biotechnology, Japan. All rights reserved.
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