期刊
JOURNAL OF BIOPHOTONICS
卷 8, 期 5, 页码 382-391出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.201400007
关键词
tissue tolerable plasma (TTP); octenidine dihydrochloride (ODC); antiseptic efficacy; wound disinfection; chronic wounds
资金
- German Ministry of Education and Research (BMBF) [13N9779]
Potential antimicrobial effects of sequential applications of tissue-tolerable plasma (TTP) and the conventional liquid antiseptic octenidine dihydrochloride (ODC) were investigated. 34 patients with chronic leg ulcers were treated with TTP, ODC or a combination of both. The bacterial colonization was measured semi-quantitatively before and immediately after treatment and changes in the microbial strains' compositions before and after antiseptic treatments were analyzed. All antiseptic procedures reduced the bacterial counts significantly. The sequential application of TTP and ODC displayed the highest antimicrobial efficacy. The combined use of TTP and conventional antiseptics might represent the most efficient strategy for antiseptic treatment of chronic wounds.
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