相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Explaining temporal trends in annualised relapse rates in placebo groups of randomised controlled trials in relapsing multiple sclerosis: systematic review and meta-regression
Simon M. Steinvorth et al.
MULTIPLE SCLEROSIS JOURNAL (2013)
Shrinkage estimation in two-stage adaptive designs with midtrial treatment selection
Maximo Carreras et al.
STATISTICS IN MEDICINE (2013)
Group sequential enrichment design incorporating subgroup selection
Baldur P. Magnusson et al.
STATISTICS IN MEDICINE (2013)
An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection
Nick Parsons et al.
COMPUTATIONAL STATISTICS & DATA ANALYSIS (2012)
Inflation in the number of eligibility criteria for industry-sponsored phase II cancer clinical trial: Illustration over a 20-year period
Stephanie Clisant et al.
CONTEMPORARY CLINICAL TRIALS (2012)
A conditional error function approach for subgroup selection in adaptive clinical trials
T. Friede et al.
STATISTICS IN MEDICINE (2012)
Optimizing randomized trial designs to distinguish which subpopulations benefit from treatment
M. Rosenblum et al.
BIOMETRIKA (2011)
An adaptive seamless phase II/III design for oncology trials with subpopulation selection using correlated survival endpoints
Martin Jenkins et al.
PHARMACEUTICAL STATISTICS (2011)
New Strategies for Treatment of KRAS Mutant Metastatic Colorectal Cancer
Hans Prenen et al.
CLINICAL CANCER RESEARCH (2010)
Adjusted significance levels for subgroup analyses in clinical trials
Bart Spiessens et al.
CONTEMPORARY CLINICAL TRIALS (2010)
Design and Analysis Considerations in Clinical Trials With a Sensitive Subpopulation
Yan D. Zhao et al.
STATISTICS IN BIOPHARMACEUTICAL RESEARCH (2010)
Adaptive patient enrichment designs in therapeutic trials
Sue-Jane Wang et al.
BIOMETRICAL JOURNAL (2009)
Exploring changes in treatment effects across design stages in adaptive trials
Tim Friede et al.
PHARMACEUTICAL STATISTICS (2009)
Confirmatory adaptive designs with Bayesian decision tools for a targeted therapy in oncology
Werner Brannath et al.
STATISTICS IN MEDICINE (2009)
Unbiased estimation of selected treatment means in two-stage trials
Jack Bowden et al.
BIOMETRICAL JOURNAL (2008)
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
Rafael G. Amado et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
A method for testing a prespecified subgroup in clinical trials
Yang Song et al.
STATISTICS IN MEDICINE (2007)
Biomarker-adaptive threshold design: A procedure for evaluating treatment with possible biomarker-defined subset effect
Wenyu Jiang et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Approaches to evaluation of treatment effect in randomized clinical trials with genomic subset
Sue-Jane Wang et al.
PHARMACEUTICAL STATISTICS (2007)
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
Eric Van Cutsem et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
The design of simulation studies in medical statistics
Andrea Burton et al.
STATISTICS IN MEDICINE (2006)
Adaptive designs in clinical drug development - An Executive Summary of the PhRMA Working Group
Paul Gallo et al.
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2006)
Operational challenges in adaptive design implementation
P Gallo
PHARMACEUTICAL STATISTICS (2006)
Point estimates and confidence regions for sequential trials involving selection
N Stallard et al.
JOURNAL OF STATISTICAL PLANNING AND INFERENCE (2005)
Adaptive signature design: An adaptive clinical trial design for generating and prospectively testing a gene expression signature for sensitive patients
B Freidlin et al.
CLINICAL CANCER RESEARCH (2005)
Subgroup analyses in randomized clinical trials: Statistical and regulatory issues
JM Grouin et al.
JOURNAL OF BIOPHARMACEUTICAL STATISTICS (2005)
Recursive combination tests
W Brannath et al.
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION (2002)
Adaptive group sequential designs for clinical trials:: Combining the advantages of adaptive and of classical group sequential approaches
HH Müller et al.
BIOMETRICS (2001)
分享论文
