期刊
JOURNAL OF BIONIC ENGINEERING
卷 7, 期 -, 页码 S30-S35出版社
SPRINGER SINGAPORE PTE LTD
DOI: 10.1016/S1672-6529(09)60214-6
关键词
zinc oxide film; biosensor; nanocomposite film; sol-gel
资金
- Directorate For Engineering
- Div Of Civil, Mechanical, & Manufact Inn [1030689] Funding Source: National Science Foundation
Nanocrystalline ZnO and ZnO/PVP nanocomposite films have been prepared by the sol-gel dip-coating technique from zinc acetate precursor on silicon wafer and Pyrex glass substrates. The films were characterized using atomic force microscopy for morphology, and X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy for chemical analysis. Thermally untreated and annealed films were studied in order to analyze the influence of temperature on the formation and properties of the films. The films have a uniform void-free surface and the grain size increases with the annealing temperature. The cell viability assays indicate that the growth rate of BPH cells incubated in the presence of ZnO was significantly reduced (35% of the control) compared to that of untreated controls, indicating antibacterial activity of ZnO as a result of the generation of hydrogen peroxide. The sensor characteristic of ZnO/PVP nanocomposite was also demonstrated by measuring the change in conductivity Upon exposure to superoxide anion radical..
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