期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 15, 期 4, 页码 -出版社
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3475958
关键词
optical tweezers; single-molecule studies; molecular motors; single-cell studies; microfluidics; Raman spectroscopy; optical sorting; optical stretching
资金
- UK Engineering and Physical Sciences Research Council
- EU Network of Excellence
- Royal Society
The biomedical sciences have benefited immensely from photonics technologies in the last 50 years. This includes the application of minute forces that enable the trapping and manipulation of cells and single molecules. In terms of the area of biophotonics, optical manipulation has made a seminal contribution to our understanding of the dynamics of single molecules and the microrheology of cells. Here we present a review of optical manipulation, emphasizing its impact on the areas of single-molecule studies and single-cell biology, and indicating some of the key experiments in the fields. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3475958]
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