期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 15, 期 2, 页码 -出版社
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3339953
关键词
transverse flow; photoacoustic tomography; Doppler bandwidth broadening
资金
- NCI NIH HHS [U54 CA136398] Funding Source: Medline
- NIBIB NIH HHS [R01 EB008085, R01 EB000712] Funding Source: Medline
- NINDS NIH HHS [R01 NS46214, R01 NS046214] Funding Source: Medline
We propose a new method to measure transverse flow velocity based on photoacoustic Doppler bandwidth broadening, which is determined by the geometry of the probe-beam and the velocity of the transverse flow. By exploiting pulsed laser excitation and raster motor scanning, three-dimensional structure and flow velocity can be imaged simultaneously. In addition, the flow direction can be determined with bidirectional scanning. In a flowing suspension of red-dyed microspheres (diameter: 6 Am), transverse flow speeds ranging from 0 to 2.5 mm/s as well as flow direction were measured. A cross-sectional flow image was also obtained with the tube laid in a zigzag pattern. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3339953]
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