期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 15, 期 6, 页码 -出版社
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.3509113
关键词
photoacoustics; Doppler effect; flow; medical imaging
资金
- Israeli Science Foundation (ISF)
- Israel Academy of Sciences and Humanities
- Weinstein Research Institute for Signal Processing in Tel-Aviv University
We demonstrate the use of tone-burst excitation and time-gated spectral analysis for photoacoustic Doppler mapping of flow in an unperturbed vessel phantom and in a vessel with a spatially varying lumen. The method, which mimics pulsed Doppler ultrasound, enables simultaneous measurement of axial position and flow as well as complete characterization of the Doppler spectrum over a wide range of mean velocities (3.5 to 200 mm/s). To generate the required optical excitation, a continuous cw laser source followed by an external electro-optic modulator is used. Stenoses at various levels are emulated in a C-flex tube with a flowing suspension of micrometer-scale carbon particles. Two-dimensional maps of spectral content versus axial position at different points along the vessel and for various levels of perturbations demonstrate the potential use of the method for characterization of flow irregularities. (C) 2010 Society of Photo-Optical Instrumentation Engineers, [DOI: 10.1117/1.3509113]
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