期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
卷 102, 期 7, 页码 1580-1594出版社
WILEY
DOI: 10.1002/jbm.b.33158
关键词
cell adhesion; cell-material interactions; surface analysis; tissue engineering
资金
- National Research Foundation of Korea, Ministry of Education, Science, and Technology (MEST) [NRF-2012R1A2A2A01017435]
- Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea [A120942]
- Korea Health Promotion Institute [HI12C0851020014] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2012R1A2A2A01017435, 22A20130000065] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Cellular behavior can be influenced by the chemical and physical surface characteristics of biomedical substrates. To understand the relationships between various topographical surface patterns and cellular activities, various types of pattern models have been developed and examined in a range of sizes (microscale, nanoscale, and hierarchical structures consisting of both) and shapes (pillar, hole, groove, grate, grid, and island). Here, we review fabrication methods for obtaining physically patterned microscale and nanoscale surfaces, and discuss the relationships between cellular responses and physically patterned surfaces, which could be applied to various biomedical scaffolds used in tissue engineering applications. (C) 2014 Wiley Periodicals, Inc.
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