期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
卷 85B, 期 2, 页码 361-367出版社
WILEY-LISS
DOI: 10.1002/jbm.b.30954
关键词
atomic force microscopy; contact lens; degradation; polymer; surface analysis
Purpose: The aim of this study was to analyze surface changes of three silicone-hydrogel contact lenses after daily wear. The lenses used in this study were balafilcon A, lotrafilcon B (both surface-treated), and galyfilcon A (non surface-treated). Methods: To understand how and where proteins, lipids, and other contaminants change contact lenses, surface roughness was assessed through Atomic Force Microscopy Tapping Mode (TM). Roughness parameters were Mean Surface roughness (R-a), Mean-square-roughness (R-q), and Maximum roughness (R-max). The surface topography of unworn and worn lenses was also mapped in great detail. Results: Contact lenses roughness parameters exhibited different values before and after wear and the surface appearance also changed. After wear, balafilcon A and galyfilcon A showed a significant increase on surface roughness parameters, being this increase more accentuated to galyfilcon A. In lotrafilcon B materials no significant changes were observed with wear. Conclusions: The present study suggests that surface treatment of silicone-hydrogel contact lenses can play a role in the prevention of a significant increase in roughness, and contribute to the better clinical tolerance of these lenses. (c) 2007 Wiley Periodicals, Inc.
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