期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
卷 99A, 期 4, 页码 676-683出版社
WILEY
DOI: 10.1002/jbm.a.33218
关键词
antibacterial; nanofibers; photoactive; singlet oxygen; hydrogen peroxide
资金
- Czech Science Foundation [P208/10/1678]
- Ministry of Health [IGA NS/10093]
- Ministry of Education, Youth and Sports of the Czech Republic [MSM 0021620857]
Electrospun polymeric nanofiber materials doped with 5,10,15,20-tetraphenylporphyrin (TPP) photosensitizer were prepared from four different polymers and were characterized with microscopic methods, steady-state, and time-resolved fluorescence and absorption spectroscopy. The polymers used included polyurethane Larithane (TM) (PUR), polystyrene (PS), polycaprolactone (PCL), and polyamide 6 (PA6). The antibacterial activity of all nanofiber materials against E. coli was activated by visible light and it was dependent on oxygen permeability/diffusion coefficients and the diameter of the polymeric nanofibers. This activity is based on oxidation ability of singlet oxygen O-2((1)Delta(g)) that is generated upon irradiation. All tested nanofiber materials exhibited prolonged antibacterial properties, even in the dark after long-duration irradiation. The post-irradiation effect was explained by the photogeneration of H2O2, which provided the material with long-lasting antibacterial properties. (C) 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 99A: 676-683, 2011.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据