期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
卷 88A, 期 3, 页码 823-831出版社
WILEY
DOI: 10.1002/jbm.a.32033
关键词
direct laser fabrication; dental implant; cytocompatibility; surface analysis; stereoimaging
Direct laser fabrication (DLF) allows solids with complex geometry to be produced by sintering metal powder particles in a focused laser beam. In this study, 10 Ti6Al4V alloy model dental root implants were obtained by DLF, and surface characterization was carried out using stereo scanning electron microscopy to produce 3D reconstructions. The surfaces were extremely irregular, with similar to 100 mu m deep, narrow intercommunicating crevices, shallow depressions and deep, rounded pits of widely variable shape and size, showing ample scope for interlocking with the host bone. Roughness parameters were as follows: R-t, 360.8 mu m; R-z, 358.4 mu m; R-a, 67.4 mu m; and R-q, 78.0 mu m. Disc specimens produced by DLF with an identically prepared Surface were used for biocompatibility studies with rat calvarial osteoblasts: After 9 days, cells had attached and spread on the DLF surface, spanning across the crevices, and voids. Cell density was similar to that on a commercial rough microtextured Surface but lower than on commercial smooth machined and smooth-textured grit-blasted, acid-etched surfaces. Human fibrin clot extension on the DLF surface was slightly improved by inorganic acid etching to increase the microroughness. With further refinements, DLF could be an economical means of manufacturing implants from titanium alloys. (C) 2008 Wiley Periodicals, Inc. J Biomed Mater Res 88A: 823-831, 2009
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