期刊
JOURNAL OF BIOMECHANICS
卷 46, 期 4, 页码 658-661出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2012.11.049
关键词
Allografts; Biomechanics; Anterior Cruciate Ligament (ACL); Electron beam irradiation
资金
- foundation item of Key Program of Natural Science Foundation of Shandong Province [Z2008C10]
The electron beam (Ebeam) irradiation has begun to be considered as an efficient alternative to gamma irradiation in the sterilization of allografts in the reconstruction of anterior cruciate ligament The purpose of this study was to evaluate the biomechanical properties of human tendons after exposure to electron beam and free radical scavenger ascorbate. Forty human flexor digitorum superficialis tendons were prepared from five fresh cadavers and divided randomly into four groups: A, fresh (0 kGy); B, 50 kGy Ebeam irradiation; C, fractionated 50 kGy Ebeam irradiation; D, fractionated 50 kGy Ebeam on ascorbate-treated tendons. The fractionation of 50 kGy was achieved by repeated irradiation of 2.5 kGy for 20 repetitions. Biomechanical properties were analyzed during load-to-failure testing. The fresh tendons were found to be significant different in ultimate load, ultimate elongation relative to tendons in group B. Statistical differences were found between group B and C in ultimate load. No differences were detected between group A and C in all the parameters. Compare tendons in group C and D, significant differences were found in ultimate load and ultimate stress. It is recommended that fractionated 50 kGy electron beam irradiation and free radical scavenger ascorbate should be applied in the sterilization of allografts tendons. (c) 2012 Elsevier Ltd. All rights reserved.
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