Modelling adaptative volumetric finite growth in patient-specific residually stressed arteries

Understanding the functional performance of vascular tissue is taking a rising importance due to the increasing impact of cardiovascular diseases in developed countries. Currently available medical imaging acquisition techniques, combined with computer modelling allow patient-specific simulations of customized geometries that may help in medical diagnosis and therapeutic treatment. In this work we show methodology to develop patient-specific simulations. Particular features of arteries such as their multilayered structure, as well as the non-linear behaviour of the arterial tissue are considered. A strategy based on the decomposition of the deformation gradient tensor is followed in order to include residual stresses in the real geometry. By means of this technique, it is also possible to model the adaptative growth of the artery neglecting the developing process from the embryo state. (C) 2008 Elsevier Ltd. All rights reserved.