期刊
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
卷 19, 期 5, 页码 653-664出版社
TAYLOR & FRANCIS LTD
DOI: 10.1163/156856208784089607
关键词
electrospinning; silk fibroin; nanofibrous tubular scaffold; characterization
资金
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB003210, P41EB002520] Funding Source: NIH RePORTER
- NIBIB NIH HHS [P41 EB002520-05, EB003210, R01 EB003210-06, EB002520, P41 EB002520, R01 EB003210] Funding Source: Medline
Electrospinning was used to fabricate non-woven nanofibrous tubular scaffolds from Bombyx mori silk fibroin using an all aqueous process. Cell studies and mechanical characterization tests were performed on the electrospun silk tubes to assess the viability of their usage in bioengineering small-diameter vascular grafts. Human endothelial cells and smooth muscle cells were successfully cultured on the electrospun silk. Mechanical characterization tests demonstrated burst strength sufficient to withstand arterial pressures and tensile properties comparable to native vessels. These cellular and mechanics outcomes demonstrate potential utility of these electrospun silk scaffolds for small-diameter vascular grafts.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据