期刊
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
卷 14, 期 8, 页码 1301-1311出版社
SPRINGER
DOI: 10.1007/s00775-009-0575-8
关键词
Copper-nitrosyl complex; Copper peroxynitrite; Biological copper; Density functional theory calculations; Phenol oxidation or nitration
资金
- NIDDK NIH HHS [R37 DK031450, DK31450, R01 DK031450, R37 DK031450-29] Funding Source: Medline
- NIGMS NIH HHS [R01 GM028962-29, R01 GM028962, R37 GM028962, GM28962] Funding Source: Medline
Reaction of nitrogen monoxide with a copper(I) complex possessing a tridentate alkylamine ligand gives a Cu(I)-(center dot NO) adduct, which when exposed to dioxygen generates a peroxynitrite (O=NOO-)-Cu(II) species. This undergoes thermal transformation to produce a copper(II) nitrito (NO2 (-)) complex and 0.5 mol equiv O-2. In the presence of a substituted phenol, the peroxynitrite complex effects oxidative coupling, whereas addition of chloride ion to dissociate the peroxynitrite moiety instead leads to phenol ortho nitration. Discussions include the structures (including electronic description) of the copper-nitrosyl and copper-peroxynitrite complexes and the formation of the latter, based on density functional theory calculations and accompanying spectroscopic data.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据