相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand
Amy D. Gelinas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Therapeutic Targeting of the Interleukin-6 Receptor
Toshio Tanaka et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Interleukin-6 signaling pathway in targeted therapy for cancer
Yuqi Guo et al.
CANCER TREATMENT REVIEWS (2012)
RNA-Based Therapeutics: Current Progress and Future Prospects
John C. Burnett et al.
CHEMISTRY & BIOLOGY (2012)
Hitting a complex target: an update on interleukin-6 trans-signalling
Georg H. Waetzig et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
Stefan Rose-John
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)
Targeting Interleukin-6: All the Way to Treat Autoimmune and Inflammatory Diseases
Toshio Tanaka et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)
Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets
Douglas R. Davies et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The pro- and anti-inflammatory properties of the cytokine interleukin-6
Juergen Scheller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
Simon A. Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Tocilizumab for Rheumatoid Arthritis: A Cochrane Systematic Review
Jasvinder A. Singh et al.
JOURNAL OF RHEUMATOLOGY (2011)
Discovery and Development of Therapeutic Aptamers
P. R. Bouchard et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
Interleukin-6 in bone metastasis and cancer progression
Tasnim Ara et al.
EUROPEAN JOURNAL OF CANCER (2010)
IL-6: from its discovery to clinical applications
Tadamitsu Kishimoto
INTERNATIONAL IMMUNOLOGY (2010)
Expanding the Chemistry of DNA for in Vitro Selection
Jonathan D. Vaught et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Averting inflammation by targeting the cytokine environment
Manfred Kopf et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Aptamers as therapeutics
Anthony D. Keefe et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
Larry Gold et al.
PLOS ONE (2010)
Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor
Jean-Michel Dayer et al.
RHEUMATOLOGY (2010)
Biosensors for biomarkers in medical diagnostics
M. Mascini et al.
BIOMARKERS (2008)
Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease
Norihiro Nishimoto et al.
BLOOD (2008)
A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor
M. Y. Chan et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2008)
Interieukin-6: a new therapeutic target
Josef S. Smolen et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Pegaptanib for neovascular age-related macular degeneration
ES Gragoudas et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Anti-interleukin 6 receptor antibody treatment in rheumatic disease
N Nishimoto et al.
ANNALS OF THE RHEUMATIC DISEASES (2000)
Anti-L-selectin aptamers:: Binding characteristics, pharmacokinetic parameters, and activity against an intravascular target in vivo
SR Watson et al.
ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT (2000)