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注意:仅列出部分参考文献,下载原文获取全部文献信息。BACE1 Regulates Hippocampal Astrogenesis via the Jagged1-Notch Pathway
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Reticulon family members modulate BACE1 activity and amyloid-β peptide generation
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The notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent γ-secretase cleavage
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A non-amyloidogenic function of BACE-2 in the secretory pathway
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β-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain
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Glul1 site cleavage and N-terminally truncated Aβ production upon BACE overexpression
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BACE2 functions as an alternative α-secretase in cells
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Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation
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BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein
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