相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cell division in apicomplexan parasites
Maria E. Francia et al.
NATURE REVIEWS MICROBIOLOGY (2014)
Interrogating a Hexokinase-Selected Small-Molecule Library for Inhibitors of Plasmodium falciparum Hexokinase
Michael T. Harris et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity
Rose-Laure Indorato et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Recent advances in malaria drug discovery
Marco A. Biamonte et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents
Hala Bakr El-Nassan
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Kinesin-5: Cross-bridging mechanism to targeted clinical therapy
Edward J. Wojcik et al.
GENE (2013)
Transition State Analogues of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases
Yong Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Discovery of Novel and Ligand-Efficient Inhibitors of Plasmodium falciparum and Plasmodium vivax N-Myristoyltransferase
Mark D. Rackham et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Antimitotic herbicides bind to an unidentified site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites
Enda Dempsey et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2013)
Identification of inhibitors of Plasmodium falciparum gametocyte development
Sandra Duffy et al.
MALARIA JOURNAL (2013)
Cellular Effects of Curcumin on Plasmodium falciparum Include Disruption of Microtubules
Rimi Chakrabarti et al.
PLOS ONE (2013)
The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases
Thomas Spangenberg et al.
PLOS ONE (2013)
Quinolone-3-Diarylethers: A New Class of Antimalarial Drug
Aaron Nilsen et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Discovery of a Plasmodium falciparum Glucose-6-phosphate Dehydrogenase 6-phosphogluconolactonase Inhibitor (R,Z)-N-((1-Ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) That Reduces Parasite Growth in Vitro
Janina Preuss et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Malaria resurgence: a systematic review and assessment of its causes
Justin M. Cohen et al.
MALARIA JOURNAL (2012)
The global pipeline of new medicines for the control and elimination of malaria
Melinda P. Anthony et al.
MALARIA JOURNAL (2012)
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Yongyuth Yuthavong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
SATe-II: Very Fast and Accurate Simultaneous Estimation of Multiple Sequence Alignments and Phylogenetic Trees
Kevin Liu et al.
SYSTEMATIC BIOLOGY (2012)
Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers
Vasant Muralidharan et al.
NATURE COMMUNICATIONS (2012)
Minimum Significant Ratio of Selectivity Ratios (MSRSR) and Confidence in Ratio of Selectivity Ratios (CRSR): Quantitative Measures for Selectivity Ratios Obtained by Screening Assays
Eric R. Goedken et al.
JOURNAL OF BIOMOLECULAR SCREENING (2012)
Drug-resistant malaria: Molecular mechanisms and implications for public health
Ines Petersen et al.
FEBS LETTERS (2011)
The progression of the intra-erythrocytic cell cycle of Plasmodium falciparum and the role of the centriolar plaques in asynchronous mitotic division during schizogony
David E. Arnot et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2011)
Loop 5-directed Compounds Inhibit Chimeric Kinesin-5 Motors IMPLICATIONS FOR CONSERVED ALLOSTERIC MECHANISMS
Liqiong Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Methotrexate Is Highly Potent Against Pyrimethamine-Resistant Plasmodium vivax
Mallika Imwong et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential
Jose M. Coteron et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Exploring the Intermediate States of ADP-ATP Exchange: A Simulation Study on Eg5
Wei Zhang
JOURNAL OF PHYSICAL CHEMISTRY B (2011)
Recent Developments in the Medicinal Chemistry and Therapeutic Potential of Dihydroorotate Dehydrogenase (DHODH) Inhibitors
V. K. Vyas et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2011)
ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism
Courtney L. Parke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Allosteric Drug Discrimination Is Coupled to Mechanochemical Changes in the Kinesin-5 Motor Core
Elizabeth D. Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model
Michael L. Booker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Low-Complexity Regions in Plasmodium falciparum: Missing Links in the Evolution of an Extreme Genome
Martine M. Zilversmit et al.
MOLECULAR BIOLOGY AND EVOLUTION (2010)
The Molecular Mechanism of Action of Artemisinin-The Debate Continues
Paul M. O'Neill et al.
MOLECULES (2010)
Thousands of chemical starting points for antimalarial lead identification
Francisco-Javier Gamo et al.
NATURE (2010)
Chemical genetics of Plasmodium falciparum
W. Armand Guiguemde et al.
NATURE (2010)
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E
Kenneth W. Wood et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
NSC 622124 Inhibits Human Eg5 and Other Kinesins via Interaction with the Conserved Microtubule-Binding Site
Sarah S. Learman et al.
BIOCHEMISTRY (2009)
Enabling IMaC purification of low abundance recombinant proteins from E. coli lysates
Audur Magnusdottir et al.
NATURE METHODS (2009)
Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP
Keith W. Rickert et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Cloning, enzyme characterization of recombinant human Eg5 and the development of a new inhibitor
Lei Yang et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2008)
Targeting the Kinesin Spindle Protein: Basic Principles and Clinical Implications
Vasiliki Sarli et al.
CLINICAL CANCER RESEARCH (2008)
Centrins, Cell Cycle Regulation Proteins in Human Malaria Parasite Plasmodium falciparum
Babita Mahajan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5
Salvatore DeBonis et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Microtubule inhibitors as a potential treatment for malaria
Barbara Kappes et al.
FUTURE MICROBIOLOGY (2007)
Targeting purine and pyrimidine metabolism in human apicomplexan parasites
John E. Hyde
CURRENT DRUG TARGETS (2007)
S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression
Dimitrios A. Skoufias et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Development and biological evaluation of potent and specific inhibitors of mitotic kinesin eg5
M Gartner et al.
CHEMBIOCHEM (2005)
Disparity in allosteric interactions of monastrol with Eg5 in the presence of ADP and ATP: a difference FT-IR investigation
EJ Wojcik et al.
BIOCHEMISTRY (2004)
A standardized kinesin nomenclature
CJ Lawrence et al.
JOURNAL OF CELL BIOLOGY (2004)
SWISS-MODEL: an automated protein homology-modeling server
T Schwede et al.
NUCLEIC ACIDS RESEARCH (2003)
Low-complexity segments in Plasmodium falciparum proteins are primarily nucleic acid level adaptations
HY Xue et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2003)
Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix
TM Kapoor et al.
JOURNAL OF CELL BIOLOGY (2001)
T-Coffee: A novel method for fast and accurate multiple sequence alignment
C Notredame et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)