相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis
Kristin Franke et al.
BLOOD (2013)
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress
Rashim Pal Singh et al.
BLOOD (2013)
Regulation of erythropoiesis by hypoxia-inducible factors
Volker H. Haase
BLOOD REVIEWS (2013)
Erythrocytosis and Pulmonary Hypertension in a Mouse Model of Human HIF2A Gain of Function Mutation
Qiulin Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Prolyl Hydroxylase Domain Protein 2 (PHD2) Binds a Pro-Xaa-Leu-Glu Motif, Linking It to the Heat Shock Protein 90 Pathway
Daisheng Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes
Nicolas Skuli et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
The HIF Pathway and Erythrocytosis
Frank S. Lee et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
HIF1α synergizes with glucocorticoids to promote BFU-E progenitor self-renewal
Johan Flygare et al.
BLOOD (2011)
Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation
Federico Formenti et al.
FASEB JOURNAL (2011)
Regulation of erythropoietin production
Wolfgang Jelkmann
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
Pinelopi P. Kapitsinou et al.
BLOOD (2010)
Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease
Hajime Akada et al.
BLOOD (2010)
Integrity of the prolyl hydroxylase domain protein 2:erythropoietin pathway in aging mice
Xiping Li et al.
BLOOD CELLS MOLECULES AND DISEASES (2010)
Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions
Karl R. Degenhardt et al.
DEVELOPMENTAL BIOLOGY (2010)
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
Michele M. Hickey et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
Amar J. Majmundar et al.
MOLECULAR CELL (2010)
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
Yoji Andrew Minamishima et al.
SCIENCE (2010)
Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
Massimiliano Mazzone et al.
CELL (2009)
Biochemical Characterization of Human Prolyl Hydroxylase Domain Protein 2 Variants Associated with Erythrocytosis
Melissa B. Pappalardi et al.
BIOCHEMISTRY (2008)
Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
Kotaro Takeda et al.
BLOOD (2008)
Repression via the GATA box is essential for tissue-specific erythropoietin gene expression
Naoshi Obara et al.
BLOOD (2008)
Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2α mutation
Daniel P. Gale et al.
BLOOD (2008)
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
Yoji Andrew Minamishima et al.
BLOOD (2008)
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
William G. Kaelin et al.
MOLECULAR CELL (2008)
Brief Report: PHD2 Mutation and Congenital Erythrocytosis with Paraganglioma
Charline Ladroue et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2α signaling and splenic erythropoiesis
Michele M. Hickey et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove
Melanie J. Percy et al.
BLOOD (2007)
Acute postnatal ablation of Hif-2α results in anemia
Michaela Gruber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2
Kotaro Takeda et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology
Thomas G. Smith et al.
PLOS MEDICINE (2006)
VE-cadherin-Cre-recombinase transgenic mouse: A tool for lineage analysis and gene deletion in endothelial cells
JA Alva et al.
DEVELOPMENTAL DYNAMICS (2006)
A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis
MJ Percy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
FEF-2α regulates murine hematopoietic development in an erythropoietin-dependent manner
M Scortegagna et al.
BLOOD (2005)
Pax3 functions at a nodal point in melanocyte stem cell differentiation
D Lang et al.
NATURE (2005)
Statistics review 12: Survival analysis
V Bewick et al.
CRITICAL CARE (2004)
Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
CJ Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
A highly efficient recombineering-based method for generating conditional knockout mutations
PT Liu et al.
GENOME RESEARCH (2003)
Transgenic mice with hematopoietic and lymphoid specific expression of Cre
J de Boer et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
SO Ang et al.
NATURE GENETICS (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Recombineering: A powerful new tool for mouse functional genomics
NG Copeland et al.
NATURE REVIEWS GENETICS (2001)
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
F Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
分享论文
