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Anjan P. Pandey et al.
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Wei Wang et al.
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Malte Drescher et al.
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Becket Greten-Harrison et al.
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Jacqueline Burre et al.
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Christina R. Bodner et al.
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Allan Chris M. Ferreon et al.
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Allison Dickey et al.
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Malte Drescher et al.
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Tomoki Kuwahara et al.
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Malte Drescher et al.
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Broken helix in vesicle and micelle-bound α-synuclein:: Insights from site-directed spin labeling-EPR experiments and MD simulations
Marco Bortolus et al.
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SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs
Tanvir R. Shaikh et al.
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Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes
R. A. Gangani D. Silva et al.
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Structure of membrane-bound α-synuclein from site-directed spin labeling and computational refinement
Christine C. Jao et al.
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Min Chen et al.
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α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
Antony A. Cooper et al.
SCIENCE (2006)
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Elizabeth Rhoades et al.
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Structure and dynamics of micelle-bound human α-synuclein
TS Ulmer et al.
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The determination of pair distance distributions by pulsed ESR using Tikhonov regularization
YW Chiang et al.
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Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP
DD Song et al.
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Causal relation between α-synuclein gene duplication and familial Parkinson's disease
P Ibáñez et al.
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CC Jao et al.
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TF Outeiro et al.
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AB Singleton et al.
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A Der-Sarkissian et al.
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A broken α-helix in folded α-synuclein
S Chandra et al.
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Golgi fragmentation occurs in the cells with prefibrillar α-synuclein aggregates and precedes the formation of fibrillar inclusion
N Gosavi et al.
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Generation of high curvature membranes mediated by direct endophilin bilayer interactions
K Farsad et al.
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MB Feany et al.
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A Abeliovich et al.
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