Ca2+-dependent Transcriptional Control of Ca2+ Homeostasis

Intracellular free Ca2+ ions regulate many cellular functions, and in turn, the cell devotes many genes/proteins to keep tight control of the level of intracellular free Ca2+. Here, we review recent work on Ca2+- dependent mechanisms and effectors that regulate the transcription of genes encoding proteins involved in the maintenance of the homeostasis of Ca2+ in the cell.