相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
Sung-Jun Park et al.
CELL (2012)
Regulation of SIRT1 activity by genotoxic stress
Jian Yuan et al.
GENES & DEVELOPMENT (2012)
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
Carles Canto et al.
PHARMACOLOGICAL REVIEWS (2012)
Sirtuin 1 (SIRT1) Protein Degradation in Response to Persistent c-Jun N-terminal Kinase 1 (JNK1) Activation Contributes to Hepatic Steatosis in Obesity
Zhanguo Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
Simon Schenk et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+
Zachary Gerhart-Hines et al.
MOLECULAR CELL (2011)
Peptide Switch Is Essential for Sirt1 Deacetylase Activity
Hyeog Kang et al.
MOLECULAR CELL (2011)
Sirtuins, Aging, and Medicine
Leonard Guarente
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Rimonabant, a Cannabinoid Receptor Type 1 Inverse Agonist, Inhibits Hepatocyte Lipogenesis by Activating Liver Kinase B1 and AMP-Activated Protein Kinase Axis Downstream of Gαi/o Inhibition
Hong Min Wu et al.
MOLECULAR PHARMACOLOGY (2011)
Mammalian Sirtuins: Biological Insights and Disease Relevance
Marcia C. Haigis et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Repression of estrogen receptor β function by putative tumor suppressor DBC1
Satoshi Koyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Identification of DBC1 as a transcriptional repressor for BRCA1
H. Hiraike et al.
BRITISH JOURNAL OF CANCER (2010)
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
Simon A. Hawley et al.
CELL METABOLISM (2010)
PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis
Nabil Djouder et al.
EMBO JOURNAL (2010)
HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1
Claudia C. S. Chini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
DYRK1A and DYRK3 Promote Cell Survival through Phosphorylation and Activation of SIRT1
Xiumei Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
Michelle Pacholec et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice
Carlos Escande et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Shear stress, SIRT1, and vascular homeostasis
Z. Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2
Barbara Zschoernig et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity
Dirk Beher et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2009)
CD38 as a Regulator of Cellular NAD: A Novel Potential Pharmacological Target for Metabolic Conditions
Eduardo Nunes Chini
CURRENT PHARMACEUTICAL DESIGN (2009)
Deleted in Breast Cancer 1, a Novel Androgen Receptor (AR) Coactivator That Promotes AR DNA-binding Activity
Junjiang Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage
Hyeog Kang et al.
PLOS ONE (2009)
JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity
Nargis Nasrin et al.
PLOS ONE (2009)
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
Yasukazu Nakahata et al.
CELL (2008)
A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism
Daniel Moreno et al.
FEBS LETTERS (2008)
Tissue-specific regulation of SIRT1 by calorie restriction
Danica Chen et al.
GENES & DEVELOPMENT (2008)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
Yi Liu et al.
NATURE (2008)
Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii
Kisaburo Nagamune et al.
NATURE (2008)
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao et al.
NATURE (2008)
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim et al.
NATURE (2008)
Phosphorylation Regulates SIRT1 Function
Tsutomu Sasaki et al.
PLOS ONE (2008)
Pharmacological PKA Inhibition: All May Not Be What It Seems
Andrew J. Murray
SCIENCE SIGNALING (2008)
SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
Yonghua Yang et al.
NATURE CELL BIOLOGY (2007)
The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity
Maria Thereza P. Barbosa et al.
FASEB JOURNAL (2007)
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
Eric L. Greer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols
Jonathan R. Gledhill et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
Joseph T. Rodgers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Modulation of estrogen receptor α protein level and survival function by DBC-1
Amy M. Trauernicht et al.
MOLECULAR ENDOCRINOLOGY (2007)
LKB1/STRAD promotes axon initiation during neuronal polarization
Maya Shelly et al.
CELL (2007)
Extension of human cell lifespan by nicotinamide phosphoribosyltransferase
Eric van der Veer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Zachary Gerhart-Hines et al.
EMBO JOURNAL (2007)
The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals
Javier R. Revollo et al.
CURRENT OPINION IN GASTROENTEROLOGY (2007)
Regulation of SIRT 1 mediated NAD dependent deacetylation: A novel role for the multifunctional enzyme CD38
Pinar Aksoy et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Regulation of intracellular levels of NAD: A novel role for CD38
Pinar Aksoy et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Exercise-induced alterations in extracellular signal-regulated kinase 1/2 and mammalian target of rapamycin (mTOR) signalling to regulatory mechanisms of mRNA translation in mouse muscle
David L. Williamson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
C Lugnier
PHARMACOLOGY & THERAPEUTICS (2006)
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells
L Bordone et al.
PLOS BIOLOGY (2006)
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
KA Moynihan et al.
CELL METABOLISM (2005)
Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii
EN Chini et al.
BIOCHEMICAL JOURNAL (2005)
Mechanism of human SIRT1 activation by resveratrol
MT Borra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
New roles for the LKB1→AMPK pathway
DG Hardie
CURRENT OPINION IN CELL BIOLOGY (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells
H Barata et al.
ENDOCRINOLOGY (2004)
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
JG Wood et al.
NATURE (2004)
Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase
SR Kimball et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
JR Revollo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
F Picard et al.
NATURE (2004)
Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis in 3T3-L1 adipocytes
W Yin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Glucagon and regulation of glucose metabolism
GQ Jiang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90RSK and cAMP-dependent protein kinase, but not its farnesylation at Cys433, is essential for LKB1 to suppress cell growth
GP Sapkota et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo
SP Collins et al.
BIOCHEMICAL JOURNAL (2000)
分享论文
