相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。alpha,beta-DCP-LA Selectively Activates PKC-epsilon and Stimulates Neurotransmitter Release with the Highest Potency among 4 Diastereomers
Tadashi Shimizu et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)
High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease
Emilie Cerf et al.
FASEB JOURNAL (2011)
PKC ε Activation Prevents Synaptic Loss, Aβ Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice
Jarin Hongpaisan et al.
JOURNAL OF NEUROSCIENCE (2011)
Amyloid oligomers: formation and toxicity of A beta oligomers
Masafumi Sakono et al.
FEBS JOURNAL (2010)
Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking
Rodrigo A. Fuentealba et al.
PLOS ONE (2010)
Protein Kinase C Activators as Synaptogenic and Memory Therapeutics
Miao-Kun Sun et al.
ARCHIV DER PHARMAZIE (2009)
Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid β-Protein (Aβ) Assembly from Alzheimer Disease Brains
Akihiko Noguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Reduction of β-Amyloid Levels by Novel Protein Kinase Cε Activators
Thomas J. Nelson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Protection of Neurons from Apoptosis by Apolipoprotein E-containing Lipoproteins Does Not Require Lipoprotein Uptake and Involves Activation of Phospholipase Cγ1 and Inhibition of Calcineurin
Hideki Hayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
DCP-LA Stimulates AMPA Receptor Exocytosis Through CaMKII Activation due to PP-1 Inhibition
Takeshi Kanno et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo
Sonya B. Dumanis et al.
JOURNAL OF NEUROSCIENCE (2009)
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
Guojun Bu
NATURE REVIEWS NEUROSCIENCE (2009)
Overexpression of Low-Density Lipoprotein Receptor in the Brain Markedly Inhibits Amyloid Deposition and Increases Extracellular Aβ Clearance
Jungsu Kim et al.
NEURON (2009)
The Role of Apolipoprotein E in Alzheimer's Disease
Jungsu Kim et al.
NEURON (2009)
Neuroprotective versus tumorigenic protein kinase C activators
T. J. Nelson et al.
TRENDS IN BIOCHEMICAL SCIENCES (2009)
Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks
Alexandra Bour et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
Amyloid β oligomers (Aβ1-42 globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents
Volker Nimmrich et al.
JOURNAL OF NEUROSCIENCE (2008)
ApoE promotes the proteolytic degradation of Aβ
Qingguang Jiang et al.
NEURON (2008)
A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC
Jarin Hongpaisan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Beta-amyloid disrupted synaptic vesicle endocytosis in cultured hippocampal neurons
B. L. Kelly et al.
NEUROSCIENCE (2007)
Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1
Hideki Hayashi et al.
JOURNAL OF NEUROSCIENCE (2007)
Hyperforin prevents β-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-β-deposits
M. C. Dinamarca et al.
MOLECULAR PSYCHIATRY (2006)
The linoleic acid derivative DCP-LA selectively activates PKC-ε, possibly binding to the phosphatidylserine binding site
Takeshi Kanno et al.
JOURNAL OF LIPID RESEARCH (2006)
Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons
Atul Deshpande et al.
JOURNAL OF NEUROSCIENCE (2006)
Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes
Alfred Rapp et al.
BIOCHIMIE (2006)
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné et al.
NATURE (2006)
Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling
Romain Volmer et al.
PLOS PATHOGENS (2006)
Apolipoprotein (apo) E4 enhances amyloid β peptide production in cultured neuronal cells:: ApoE structure as a potential therapeutic target
SM Ye et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Globular amyloid β-peptide1-42 oligomer -: a homogenous and stable neuropathological protein in Alzheimer's disease
S Barghorn et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Identification of conserved amino acids N-terminal of the PKCεC1b domain crucial for protein kinase Cε-mediated induction of neurite outgrowth
M Ling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein
C Lanni et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Amyloid beta peptide directly inhibits PKC activation
W Lee et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2004)
Apolipoprotein E and β-amyloid (1-42) regulation of glycogen synthase kinase-3β
A Cedazo-Mínguez et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β
M Hoshi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Role of cholesterol in synapse formation and function
FW Pfrieger
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2003)
Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients
Y Ji et al.
NEUROSCIENCE (2003)
Critical role of diacylglycerol- and phospholipid-regulated protein kinase Cε in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol
KD Mehta et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
CNS synaptogenesis promoted by glia-derived cholesterol
DH Mauch et al.
SCIENCE (2001)
Introduction of human apolipoprotein E4 domain interaction into mouse apolipoprotein E
RL Raffaï et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Behavioral phenotyping of GFAP-ApoE3 and-ApoE4 transgenic mice: ApoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology
RE Hartman et al.
EXPERIMENTAL NEUROLOGY (2001)
Protein kinase C ε suppresses Aβ production and promotes activation of α-secretase
GF Zhu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Blockade of PKCε activation attenuates phorbol ester-induced increase of α-secretase-derived secreted form of amyloid precursor protein
SW Yeon et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
Dennis J. Selkoe
JOURNAL OF ALZHEIMERS DISEASE (2001)
Regulation of amyloid precursor protein (APP) secretion by protein kinase Cα in human ntera 2 neurons (NT2N)
C Jolly-Tornetta et al.
BIOCHEMISTRY (2000)
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides
T Tokuda et al.
BIOCHEMICAL JOURNAL (2000)