相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron
Tomáš Šimůnek et al.
Pharmacological Reports (2014)
Genotoxicity of dietary, environmental and therapeutic topoisomerase II poisons is uniformly correlated to prolongation of enzyme DNA residence
Faiza M. Kalfalah et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2011)
Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity
J. Huelsenbeck et al.
CELL DEATH & DISEASE (2011)
Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy
Youyou Zhao et al.
CANCER RESEARCH (2010)
Pleiotropic Effects of Statins - Basic Research and Clinical Perspectives
Qian Zhou et al.
CIRCULATION JOURNAL (2010)
Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression
Simon A. Woodcock et al.
CURRENT BIOLOGY (2010)
A minority of foci or pan-nuclear apoptotic staining of γH2AX in the S phase after UV damage contain DNA double-strand breaks
Sebastien de Feraudy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Nuclear Import of the Small GTPase Rac1 is Mediated by the Direct Interaction with Karyopherin α2
Kirstin Sandrock et al.
TRAFFIC (2010)
Pretreatment with Statin Attenuates the Cardiotoxicity of Doxorubicin in Mice
Alexander Riad et al.
CANCER RESEARCH (2009)
Importance of Rac1 Signaling Pathway Inhibition in the Pleiotropic Effects of HMG-CoA Reductase Inhibitors
Mamunur Rashid et al.
CIRCULATION JOURNAL (2009)
Targeting the Mevalonate Pathway for Improved Anticancer Therapy
G. Fritz
CURRENT CANCER DRUG TARGETS (2009)
Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity
Masashi Yoshida et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Topoisomerase IIα-dependent and -independent apoptotic effects of dexrazoxane and doxorubicin
Tiandong Yan et al.
MOLECULAR CANCER THERAPEUTICS (2009)
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase
Sean W. Deacon et al.
CHEMISTRY & BIOLOGY (2008)
Statins use a novel Nijmegen breakage syndrome-1-dependent pathway to accelerate DNA repair in vascular smooth muscle cells
Melli Mahmoudi et al.
CIRCULATION RESEARCH (2008)
Supreme enLIGHTenment: Damage recognition and signaling in the mammalian UV response
Peter Herrlich et al.
MOLECULAR CELL (2008)
gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
Andrea Kinner et al.
NUCLEIC ACIDS RESEARCH (2008)
The DNA damage response: Ten years after
J. Wade Harper et al.
MOLECULAR CELL (2007)
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
M. F. Lavin
ONCOGENE (2007)
Topoisomerase IIβ-Mediated DNA double-strand breaks:: Implications in doxorubicin cardiotoxicity and prevention by dexrazoxane
Yi Lisa Lyu et al.
CANCER RESEARCH (2007)
Successful mitigation of delayed intestinal radiation injury using pravastatin is not associated with acute injury improvement or tumor protection
Valerie Haydont et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2007)
Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies
Anna M. Azarova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide
J. Damrot et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Clinical heart failure in a cohort of children treated with anthracyclines: A long-term follow-up study
Elvira C. van Dalen et al.
EUROPEAN JOURNAL OF CANCER (2006)
Radiation-induced DNA damage responses
Penny Jeggo et al.
RADIATION PROTECTION DOSIMETRY (2006)
H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks
Thomas M. Marti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Chromosomal damage and atherosclerosis.: A protective effect from simvastatin
F Pernice et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Lovastatin protects human endothelial cells from killing by ionizing radiation without impairing induction and repair of DNA double-strand breaks
T Nübel et al.
CLINICAL CANCER RESEARCH (2006)
The comet assay: a method to measure DNA damage in individual cells
Peggy L. Olive et al.
NATURE PROTOCOLS (2006)
DNA damage-induced cell death by apoptosis
Wynand P. Roos et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Doxorubicin paradoxically protects cardiomyocytes against iron-mediated toxicity - Role of reactive oxygen species and ferritin
G Corna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
T Stiff et al.
CANCER RESEARCH (2004)
The role of nitric oxide in anthracycline toxicity and prospects for pharmacologic prevention of cardiac damage
S Fogli et al.
FASEB JOURNAL (2004)
NBS1 and its functional role in the DNA damage response
J Kobayashi et al.
DNA REPAIR (2004)
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
Y Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair
J Hayakawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
K Rothkamm et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
CJ Bakkenist et al.
NATURE (2003)
Anthracycline-induced clinical heart failure in a cohort of 607 children: Long-term follow-up study
LCM Kremer et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
The DNA damage response: putting checkpoints in perspective
BBS Zhou et al.
NATURE (2000)
Rho GTPases and their effector proteins
AL Bishop et al.
BIOCHEMICAL JOURNAL (2000)
Rad regulates interleukin 1-induced nuclear factor κB activation in an inhibitory protein κBα-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression
CA Jefferies et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
分享论文
