4.6 Article

Multiple BH3 Mimetics Antagonize Antiapoptotic MCL1 Protein by Inducing the Endoplasmic Reticulum Stress Response and Up-regulating BH3-only Protein NOXA

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Perturbation of the Bcl-2 Network and an Induced Noxa/Bcl-xL Interaction Trigger Mitochondrial Dysfunction after DNA Damage

Hernando Lopez et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Biochemistry & Molecular Biology

The BCL-2 Family Reunion

Jerry E. Chipuk et al.

MOLECULAR CELL (2010)

Article Biochemistry & Molecular Biology

Different forms of cell death induced by putative BCL2 inhibitors

M. Vogler et al.

CELL DEATH AND DIFFERENTIATION (2009)

Article Multidisciplinary Sciences

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

Qiuyan Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

Mai Nguyen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition

Mikhail A. Nikiforov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Structural insights into the degradation of Mcl-1 induced by BH3 domains

Peter E. Czabotar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Biochemistry & Molecular Biology

The Bcl-2 apoptotic switch in cancer development and therapy

J. M. Adams et al.

ONCOGENE (2007)

Article Multidisciplinary Sciences

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

Simon N. Willis et al.

SCIENCE (2007)

Article Medicine, Research & Experimental

Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737

Victoria Del Gaizo Moore et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Biochemistry & Molecular Biology

Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins

D. Zhai et al.

CELL DEATH AND DIFFERENTIATION (2006)

Review Biochemistry & Molecular Biology

BCL-2 in the crosshairs: tipping the balance of life and death

L. D. Walensky

CELL DEATH AND DIFFERENTIATION (2006)

Article Biochemistry & Molecular Biology

Bcl-2 changes conformation to inhibit Bax oligomerization

Paulina J. Dlugosz et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Coping with stress: eIF2 kinases and translational control

RC Wek et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2006)

Article Multidisciplinary Sciences

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

T Oltersdorf et al.

NATURE (2005)

Review Biotechnology & Applied Microbiology

ER stress and the unfolded protein response

M Schröder et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)

Article Biochemistry & Molecular Biology

During apoptosis Bcl-2 changes membrane topology at both the endoplasmic reticulum mitochondria

PK Kim et al.

MOLECULAR CELL (2004)

Article Biochemistry & Molecular Biology

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

HP Harding et al.

MOLECULAR CELL (2003)

Article Biochemistry & Molecular Biology

A role for mitochondrial Bak in apoptotic response to anticancer drugs

GQ Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

A new mathematical model for relative quantification in real-time RT-PCR

MW Pfaffl

NUCLEIC ACIDS RESEARCH (2001)

Review Biochemistry & Molecular Biology

The hallmarks of cancer

D Hanahan et al.