被撤回的出版物: Effect of Ser-129 Phosphorylation on Interaction of α-Synuclein with Synaptic and Cellular Membranes (Retracted article. See vol. 295, pg. 13695, 2020)

Background: The majority of alpha-synuclein is phosphorylated at serine 129 in Lewy bodies. Results: The membrane association of PD-linked mutant alpha-synuclein, but not wild-type alpha-synuclein, was increased by serine 129 phosphorylation. Conclusion: Pathological serine 129 phosphorylation regulates membrane accumulation of mutant alpha-synuclein. Significance: The relationship of serine 129 phosphorylation to pathogenic aggregation of normal and mutant alpha-synuclein may be governed by distinct effects on phosphoprotein membrane accumulation.