4.6 Article

Chaperoning of Mutant p53 Protein by Wild-type p53 Protein Causes Hypoxic Tumor Regression

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation

Hyunjung Kim et al.

JOURNAL OF MOLECULAR BIOLOGY (2012)

Review Oncology

The role of mutant p53 in human cancer

Amanda M. Goh et al.

JOURNAL OF PATHOLOGY (2011)

Article Biochemistry & Molecular Biology

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

Jie Xu et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Multidisciplinary Sciences

p53 Amino-Terminus Region (1-125) Stabilizes and Restores Heat Denatured p53 Wild Phenotype

Anuj Kumar Sharma et al.

PLOS ONE (2009)

Article Oncology

Three Assays Show Differences in Binding of Wild-Type and Mutant p53 to Unique Gene Sequences

Uma Chandrachud et al.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2009)

Review Biochemistry & Molecular Biology

Structural biology of the tumor suppressor p53

Andreas C. Joerger et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2008)

Article Pharmacology & Pharmacy

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

Sanjeev Shangary et al.

Annual Review of Pharmacology and Toxicology (2008)

Article Biotechnology & Applied Microbiology

The genetics of the p53 pathway, apoptosis and cancer therapy

Alexei Vazquez et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Article Biochemistry & Molecular Biology

CHIP chaperones wild type p53 tumor suppressor protein

Veenu Tripathi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Biochemistry & Molecular Biology

Detection and characterization of tumor hypoxia using pO2 histography

Peter Vaupel et al.

ANTIOXIDANTS & REDOX SIGNALING (2007)

Article Oncology

p53 therapy in a patient with Li-Fraumeni syndrome

Neil Senzer et al.

MOLECULAR CANCER THERAPEUTICS (2007)

Article Biochemistry & Molecular Biology

Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis

T. Liu et al.

CELL DEATH AND DIFFERENTIATION (2007)

Article Multidisciplinary Sciences

Restoration of p53 function leads to tumour regression in vivo

Andrea Ventura et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Modeling the therapeutic efficacy of p53 restoration in tumors

Carla P. Martins et al.

Article Endocrinology & Metabolism

The DU145 human prostate carcinoma cell line harbors a temperature-sensitive allele of p53

Marcio C. Bajgelman et al.

PROSTATE (2006)

Article Biochemistry & Molecular Biology

Hypoxia and HIF-1α protect A549 cells from drug-induced apoptosis

S. E. Schnitzer et al.

CELL DEATH AND DIFFERENTIATION (2006)

Article Biochemistry & Molecular Biology

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment

Y Pan et al.

ONCOGENE (2004)

Article Biochemistry & Molecular Biology

The use of transient chromatin Immunoprecipitation assays to test models for E2F1-specific transcriptional activation

JL Lavrrar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Hypoxia attenuates the p53 response to cellular damage

M Achison et al.

ONCOGENE (2003)

Article Biotechnology & Applied Microbiology

p53 alone or in combination with antisense cyclin D1 induces apoptosis and reduces tumor size in human melanoma

ER Sauter et al.

CANCER GENE THERAPY (2002)

Article Multidisciplinary Sciences

Disassembly of transcriptional regulatory complexes by molecular chaperones

BC Freeman et al.

SCIENCE (2002)

Article Biochemistry & Molecular Biology

The 'wildtype' conformation of p53: epitope mapping using hybrid proteins

PL Wang et al.

ONCOGENE (2001)

Article Biochemistry & Molecular Biology

Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation

C Koumenis et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Stress signals utilize multiple pathways to stabilize p53

M Ashcroft et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)