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Kelly Jean Thomas et al.
HUMAN MOLECULAR GENETICS (2011)
DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells
Haigang Ren et al.
CANCER LETTERS (2010)
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6
E. Giaime et al.
CELL DEATH AND DIFFERENTIATION (2010)
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
Frits Kamp et al.
EMBO JOURNAL (2010)
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I. Irrcher et al.
HUMAN MOLECULAR GENETICS (2010)
DJ-1, PINK1, and Their Effects on Mitochondrial Pathways
Mark R. Cookson
MOVEMENT DISORDERS (2010)
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
Ling-Yang Hao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Parkinson-Linked Genes and Toxins That Affect Neuronal Cell Death Through the Bcl-2 Family
Douglas W. Ethell et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein
Yu Feng et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)
Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1
Jeff Blackinton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mitochondrial Localization of DJ-1 Leads to Enhanced Neuroprotection
Eunsung Junn et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death
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CELL DEATH AND DIFFERENTIATION (2008)
Expression and clinical role of DJ-1, a negative regulator of PTEN, in ovarian carcinoma
Ben Davidson et al.
HUMAN PATHOLOGY (2008)
The BCL-2 protein family: opposing activities that mediate cell death
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
Claire Henchcliffe et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2008)
DJ-1 decreases Bax expression through repressing p53 transcriptional activity
Jun Fan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
Eva Andres-Mateos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
DJ-1: A new comer in Parkinson's disease pathology
Cristine Alves da Costa
CURRENT MOLECULAR MEDICINE (2007)
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
Casey M. Clements et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model
Masatoshi Inden et al.
NEUROBIOLOGY OF DISEASE (2006)
Role of DJ-1 in Parkinson's disease
Nirit Lev et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2006)
Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities
Y Shinbo et al.
CELL DEATH AND DIFFERENTIATION (2006)
Bcl-x is required for proper development of the mouse substantia nigra
JM Savitt et al.
JOURNAL OF NEUROSCIENCE (2005)
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
L Zhang et al.
HUMAN MOLECULAR GENETICS (2005)
Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization
J Blackinton et al.
MOLECULAR BRAIN RESEARCH (2005)
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease
K Hedrich et al.
NEUROLOGY (2004)
DJ-1 has a role in antioxidative stress to prevent cell death
T Taira et al.
EMBO REPORTS (2004)
Differential control of apoptogis by DJ-1 in prostate benign and cancer cells
Y Hod
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
RM Canet-Avilés et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Bcl-xL sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers
SY Jeong et al.
EMBO JOURNAL (2004)
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
T Yokota et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The role of pathogenic DJ-1 mutations in Parkinson's disease
PM Abou-Sleiman et al.
ANNALS OF NEUROLOGY (2003)
Regulation of apoptosis by Bcl-2 family proteins
A Burlacu
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2003)
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
V Bonifati et al.
SCIENCE (2003)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
M Vila et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
NA Tatton
EXPERIMENTAL NEUROLOGY (2000)