相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca++ Sensors
John G. Yamauchi et al.
PLOS ONE (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Surface Plasmon Resonance Biosensor Based Fragment Screening Using Acetylcholine Binding Protein Identifies Ligand Efficiency Hot Spots (LE Hot Spots) by Deconstruction of Nicotinic Acetylcholine Receptor α7 Ligands
Gerdien E. de Kloe et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
An in vivo biosensor for neurotransmitter release and in situ receptor activity
Quoc-Thang Nguyen et al.
NATURE NEUROSCIENCE (2010)
ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments
Charles Simon Bond et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2009)
Design and expression of human α7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties
Marios Zouridakis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2009)
Single-Channel Current Through Nicotinic Receptor Produced by Closure of Binding Site C-Loop
Hai-Long Wang et al.
BIOPHYSICAL JOURNAL (2009)
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
Ryan E. Hibbs et al.
EMBO JOURNAL (2009)
Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the alpha 4 beta 2 nicotinic acetylcholine receptor
Kayoko Toshima et al.
NEUROPHARMACOLOGY (2009)
αConotoxin Arenatus IB[V11I,V16D] Is a Potent and Selective Antagonist at Rat and Human Native α7 Nicotinic Acetylcholine Receptors
Neal Innocent et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
A genetically encoded calcium indicator for chronic in vivo two-photon imaging
Marco Mank et al.
NATURE METHODS (2008)
Taking the time to study competitive antagonism
D. J. A. Wyllie et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Structure-guided drug design: Conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes
Palmer Taylor et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Circular dichroism studies of extracellular domains of human nicotinic acetylcholine receptors provide an insight into their structure
Marios Zouridakis et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2007)
Nanosecond-timescale conformational dynamics of the human α7 nicotinic acetylcholine receptor
Xiaolin Cheng et al.
BIOPHYSICAL JOURNAL (2007)
Galanthamine and non-competitive inhibitor binding to ACh-binding protein:: Evidence for a binding site on non-α-subunit interfaces of heteromeric neuronal nicotinic receptors
Scott B. Hansen et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Discovery, synthesis, and structure activity of a highly selective α7 nicotinic acetylcholine receptor antagonist
Paul Whiteaker et al.
BIOCHEMISTRY (2007)
Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists
Daniel P. Walker et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions
Todd T. Talley et al.
BIOCHEMISTRY (2006)
Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the α7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia:: Synthesis and structure-activity relationship
Donn G. Wishka et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry
JX Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Selective alpha 7 nicotinic acetylcholine receptor ligands
Anatoly Mazurov et al.
CURRENT MEDICINAL CHEMISTRY (2006)
Extracellular domain nicotinic acetylcholine receptors formed by α4 and β2 subunits
AM Person et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
SB Hansen et al.
EMBO JOURNAL (2005)
Neuronal nicotinic acetylcholine receptors: Structural revelations, target identifications, and therapeutic inspirations
AA Jensen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant
PHN Celie et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
A novel positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor:: In vitro and in vivo characterization
RS Hurst et al.
JOURNAL OF NEUROSCIENCE (2005)
Molecular dissection of tropisetron, an α7 nicotinic acetylcholine receptor-selective partial agonist
RL Papke et al.
NEUROSCIENCE LETTERS (2005)
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors
Y Bourne et al.
EMBO JOURNAL (2005)
Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence
F Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The selective α7 nicotinic acetylcholine receptor agonist PNU-282987[N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats
M Hajós et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Discovery and structure -: Activity relationship of quinuclidine benzamides as agonists of α7 nicotinic acetylcholine receptors
AL Bodnar et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
PHN Celie et al.
NEURON (2004)
Soluble, oligomeric, and ligand-binding extracellular domain of the human α7 acetylcholine receptor expressed in yeast -: Replacement of the hydrophobic cysteine loop by the hydrophilic loop of the ACh-binding protein enhances protein solubility
V Avramopoulou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The structural basis for GTS-21 selectivity between human and rat nicotinic α7 receptors
C Stokes et al.
MOLECULAR PHARMACOLOGY (2004)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Hydroxy metabolites of the Alzheimer's drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride (GTS-21): Their molecular properties, interactions with brain nicotinic receptors, and brain penetration
WR Kem et al.
MOLECULAR PHARMACOLOGY (2004)
A graphical user interface to the CCP4 program suite
E Potterton et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2003)
Identification of regions involved in the binding of α-bungarotoxin to the human α7 neuronal nicotinic acetylcholine receptor using synthetic peptides
M Marinou et al.
BIOCHEMICAL JOURNAL (2003)
α-conotoxins ImI and ImII -: Similar α7 nicotinic receptor antagonists act at different sites
M Ellison et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein
SB Hansen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structure and function in rhodopsin:: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
PJ Reeves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Comparative pharmacology of rat and human α7 nAChR conducted with net charge analysis
RL Papke et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Emerging structure of the nicotinic acetylcholine receptors
A Karlin
NATURE REVIEWS NEUROSCIENCE (2002)
Recent Progress in the Development of Subtype Selective Nicotinic Acetylcholine Receptor Ligands
P. C. Astles et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2002)
A method for soluble overexpression of the α7 nicotinic acetylcholine receptor extracellular domain
M Fischer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist
JE Macor et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor
ML Tierney et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)