相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Alternative Macrophage Activation and Metabolism
Justin I. Odegaard et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
Inflammatory links between obesity and metabolic disease
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Dynamic, M2-Like Remodeling Phenotypes of CD11c+Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice
Merav E. Shaul et al.
DIABETES (2010)
Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
John M. Wentworth et al.
DIABETES (2010)
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
Jang Hyun Choi et al.
NATURE (2010)
Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ-/-, PPARδ-/-, PPARγδ-/-, or LXRαβ-/- bone marrow
Chaitra Marathe et al.
JOURNAL OF LIPID RESEARCH (2009)
INT131: A Selective Modulator of PPARγ
Alykhan Motani et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
MBX-102/JNJ39659100, a Novel Peroxisome Proliferator-Activated Receptor-Ligand with Weak Transactivation Activity Retains Antidiabetic Properties in the Absence of Weight Gain and Edema
Francine M. Gregoire et al.
MOLECULAR ENDOCRINOLOGY (2009)
Type 2 Diabetes and Oral Antihyperglycemic Drugs
Mitchell Avery et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
Carey N. Lumeng et al.
DIABETES (2008)
A functional peroxisome proliferator-activated receptor-γ ligand-binding domain is not required for adipogenesis
Christopher J. Walkey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site
Joel S. Gordon et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
Zoltan Arany et al.
NATURE (2008)
Structural basis for the activation of PPARγ by oxidized fatty acids
Toshimasa Itoh et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
TZDs and Bone: A Review of the Recent Clinical Evidence
Ann V. Schwartz
PPAR RESEARCH (2008)
The differential interactions of peroxisome proliferator-activated receptor gamma ligands with tyr473 is a physical basis for their unique biological activities
Monica Einstein et al.
MOLECULAR PHARMACOLOGY (2008)
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus - A meta-analysis of randomized trials
A. Michael Lincoff et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
The next generation of PPAR drugs: Do we have the tools to find them?
Barry G. Shearer et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
PPARs and molecular mechanisms of transrepression
Mercedes Ricote et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Modulation of PPAR activity via phosphorylation
Katherine A. Burns et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
MAPK kinases as nucleo-cytoplasmic shuttles for PPARγ
Elke Burgermeister et al.
CELL CYCLE (2007)
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
Justin I. Odegaard et al.
NATURE (2007)
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
Steven E. Nissen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Insights into the mechanism of partial agonism -: Crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complex with two enantiomeric ligands
Giorgio Pochetti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression
Hironori Waki et al.
CELL METABOLISM (2007)
Obesity, inflammation, and insulin resistance
Steven E. Shoelson et al.
GASTROENTEROLOGY (2007)
Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes
Maria Kolak et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Inflammation and metabolic disorders
Goekhan S. Hotamisligil
NATURE (2006)
Adipocyte differentiation from the inside out
Evan D. Rosen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Inflammation and insulin resistance
Steven E. Shoelson et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
JN Feige et al.
PROGRESS IN LIPID RESEARCH (2006)
Adipocyte differentiation-related protein in human skeletal muscle: Relationship to insulin sensitivity
SA Phillips et al.
OBESITY RESEARCH (2005)
Opinion - Post-prenylation-processing enzymes as new targets in oncogenesis
AM Winter-Vann et al.
NATURE REVIEWS CANCER (2005)
PPARs: therapeutic targets for metabolic disease
JP Berger et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2005)
A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein
P Targett-Adams et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2005)
Kinase signaling cascades that modulate peroxisome proliferator-activated receptors
L Gelman et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Hic-5 regulates an epithelial program mediated by PPARγ
S Drori et al.
GENES & DEVELOPMENT (2005)
Benzoyl 2-methyl indoles as selective PPARγ modulators
JJ Acton et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Drug therapy: Thiazolidinediones
H Yki-Jarvinen
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Evidence for a potent antiinflammatory effect of rosiglitazone
P Mohanty et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Interaction of tumor necrosis factor-α- and thiazolidinedione-regulated pathways in obesity
KE Wellen et al.
ENDOCRINOLOGY (2004)
Genetic modulation of PPARγ phosphorylation regulates insulin sensitivity
SM Rangwala et al.
DEVELOPMENTAL CELL (2003)
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
HY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide
JA Willment et al.
JOURNAL OF IMMUNOLOGY (2003)
Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
SM Haffner et al.
CIRCULATION (2002)
C/EBP alpha induces adipogenesis through PPAR gamma: a unified pathway
ED Rosen et al.
GENES & DEVELOPMENT (2002)
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
HE Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
PPARγ:: a nuclear regulator of metabolism, differentiation, and cell growth
ED Rosen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice
GBT Moore et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists
JM Olefsky
JOURNAL OF CLINICAL INVESTIGATION (2000)
Peroxisome proliferator-activated receptor γ target gene encoding a novel angiopoietin-related protein associated with adipose differentiation
JC Yoon et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Degradation of the peroxisome proliferator-activated receptor γ is linked to ligand-dependent activation
S Hauser et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)