相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Immunosuppressive Cyclosporin A Activates AKT in Keratinocytes through PTEN Suppression IMPLICATIONS IN SKIN CARCINOGENESIS
Weinong Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Caffeine Confers Radiosensitization of PTEN-Deficient Malignant Glioma Cells by Enhancing Ionizing Radiation-Induced G1 Arrest and Negatively Regulating Akt Phosphorylation
Brigitte Sinn et al.
MOLECULAR CANCER THERAPEUTICS (2010)
UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes
M. Ming et al.
ONCOGENE (2010)
Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C
Mei Ming et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
ATR-Chk1 Pathway Inhibition Promotes Apoptosis after UV Treatment in Primary Human Keratinocytes: Potential Basis for the UV Protective Effects of Caffeine
Timothy P. Heffernan et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity
James E. Cleaver et al.
NATURE REVIEWS GENETICS (2009)
Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice
Yao-Ping Lu et al.
CANCER RESEARCH (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Early events in UV carcinogenesis - DNA damage, target cells and mutant p53 foci
Frank R. de Gruijl et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2008)
ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells
Yannick Auclair et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis
Susan M. Fischer et al.
MOLECULAR CARCINOGENESIS (2007)
Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4
Kyung-Soo Chun et al.
CANCER RESEARCH (2007)
Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice
Yao-Ping Lu et al.
CARCINOGENESIS (2007)
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
Anthony Renwick et al.
NATURE GENETICS (2006)
Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance
YY He et al.
ONCOGENE (2006)
Inhibition of epidermal growth factor-induced cell transformation and Akt activation by caffeine
M Nomura et al.
MOLECULAR CARCINOGENESIS (2005)
Cancer in xeroderma pigmentosum and related disorders of DNA repair
JE Cleaver
NATURE REVIEWS CANCER (2005)
Caffeine inhibits cell proliferation by G0/G1 phase arrest in JB6 cells
T Hashimoto et al.
CANCER RESEARCH (2004)
Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice\
YP Lu et al.
CANCER RESEARCH (2004)
Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling
GT Bowden
NATURE REVIEWS CANCER (2004)
Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases
D Cortez
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
EJ Brown et al.
GENES & DEVELOPMENT (2003)
p53 mutations as a marker of skin cancer risk: comparison of UVA and UVB effects
FR de Gruijl
EXPERIMENTAL DERMATOLOGY (2002)
Direct effects of caffeine and theophylline on p110δ and other phosphoinositide 3-kinases -: Differential effects on lipid kinase and protein kinase activities
LC Foukas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Deficiency in the repair of UV-induced DNA damage in human skin fibroblasts compromised for the ATM gene
MA Hannan et al.
CARCINOGENESIS (2002)
Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice
YP Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
A Hirao et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
ATR is not required for p53 activation but synergizes with p53 in the replication check-point
P Nghiem et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ten years of protein kinase B signalling: a hard Akt to follow
DP Brazil et al.
TRENDS IN BIOCHEMICAL SCIENCES (2001)
Persistent p53 mutations in single cells from normal human skin
G Ling et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation
P Nghiem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Genome maintenance mechanisms for preventing cancer
JHJ Hoeijmakers
NATURE (2001)
The DNA damage response: putting checkpoints in perspective
BBS Zhou et al.
NATURE (2000)
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems
M Liu et al.
GENES & DEVELOPMENT (2000)
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
S Matsuoka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E-2 synthesis in rat microglial cells
BL Fiebich et al.
NEUROPHARMACOLOGY (2000)