4.6 Article

Wild-type p53-induced Phosphatase 1 Dephosphorylates Histone Variant γ-H2AX and Suppresses DNA Double Strand Break Repair

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

53BP1: function and mechanisms of focal recruitment

Jennifer E. FitzGerald et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2009)

Article Genetics & Heredity

Common mechanisms of PIKK regulation

Courtney A. Lovejoy et al.

DNA REPAIR (2009)

Article Biochemistry & Molecular Biology

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

Shinichiro Nakada et al.

EMBO REPORTS (2008)

Article Biochemistry & Molecular Biology

Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase

Akinori Yoda et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

A PP4-phosphatase complex dephosphorylates γ-H2AX generated during DNA replication

Dipanjan Chowdhury et al.

MOLECULAR CELL (2008)

Review Cell Biology

ATR: an essential regulator of genome integrity

Karlene A. Cimprich et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Biochemistry & Molecular Biology

gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

Andrea Kinner et al.

NUCLEIC ACIDS RESEARCH (2008)

Review Multidisciplinary Sciences

An oncogene-induced DNA damage model for cancer development

Thanos D. Halazonetis et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D

S. Rayter et al.

ONCOGENE (2008)

Article Cell Biology

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

Elijahu Berkovich et al.

NATURE CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Wip1 phosphatase modulates ATM-dependent signaling pathways

Sathyavageeswaran Shreeram et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice

Bonnie Nannenga et al.

MOLECULAR CARCINOGENESIS (2006)

Article Biochemistry & Molecular Biology

Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase

H. Fujimoto et al.

CELL DEATH AND DIFFERENTIATION (2006)

Article Biochemistry & Molecular Biology

γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

D Chowdhury et al.

MOLECULAR CELL (2005)

Article Cell Biology

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

XB Lu et al.

GENES & DEVELOPMENT (2005)

Article Biochemistry & Molecular Biology

Substrate specificity of the human protein phosphatase 2Cδ Wip1

H Yamaguchi et al.

BIOCHEMISTRY (2005)

Review Biochemistry & Molecular Biology

The life and death of DNA-PK

SJ Collis et al.

ONCOGENE (2005)

Article Cell Biology

Phosphatases join kinases in DNA-damage response pathways

CJ Bakkenist et al.

TRENDS IN CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

A Celeste et al.

Review Oncology

ATM and related protein kinases: Safeguarding genome integrity

Y Shiloh

NATURE REVIEWS CANCER (2003)

Article Multidisciplinary Sciences

MDC1 is a mediator of the mammalian DNA damage checkpoint

GS Stewart et al.

NATURE (2003)

Article Multidisciplinary Sciences

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5

XF Qin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Genetics & Heredity

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

DV Bulavin et al.

NATURE GENETICS (2002)

Article Multidisciplinary Sciences

Genomic instability in mice lacking histone H2AX

A Celeste et al.

SCIENCE (2002)

Review Cell Biology

Cell cycle checkpoint signaling through the ATM and ATR kinases

RT Abraham

GENES & DEVELOPMENT (2001)

Review Chemistry, Multidisciplinary

Molecular reactions of protein phosphatases - Insights from structure and chemistry

MD Jackson et al.

CHEMICAL REVIEWS (2001)

Review Cell Biology

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

D Durocher et al.

CURRENT OPINION IN CELL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

DNA repair: Spot(light)s on chromatin

M Modesti et al.

CURRENT BIOLOGY (2001)

Review Genetics & Heredity

Chromosomal stability and the DNA double-stranded break connection

DC van Gent et al.

NATURE REVIEWS GENETICS (2001)

Article Biochemistry & Molecular Biology

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

TT Paull et al.

CURRENT BIOLOGY (2000)

Article Multidisciplinary Sciences

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

PR Borghesani et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)