相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
Michael P. Bokoch et al.
NATURE (2010)
Allosteric Modulators of G Protein-Coupled Receptors: Future Therapeutics for Complex Physiological Disorders
Liyun Wang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Orthosteric/Allosteric Bitopic Ligands Going Hybrid at GPCRs
Celine Valant et al.
MOLECULAR INTERVENTIONS (2009)
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P. Jeffrey Conn et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation
Shivani Ahuja et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
RHO protein regulation of contraction in the human uterus
J. Lartey et al.
REPRODUCTION (2009)
Functional selectivity through protean and biased agonism: Who steers the ship?
Terry Kenakin
MOLECULAR PHARMACOLOGY (2007)
Critical role for the second extracellular loop in the binding of both orthosteric and allosteric g protein-coupled receptor Ligands
Vimesh A. Avlani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: A perspective
Ashok K. Pullikuth et al.
CELLULAR SIGNALLING (2007)
The evasive nature of drug efficacy:: implications for drug discovery
Segolene Galandrin et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties
Emeline L. Maillet et al.
FASEB JOURNAL (2007)
Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor
J. Lartey et al.
BIOLOGY OF REPRODUCTION (2007)
An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations
Noriko Makita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation
Marco Scarselli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Novel in vitro system for functional assessment of oxytocin action
Dominic Devost et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Prostaglandin F-2 alpha and its receptor as activators of human decidua
Shintaro Makino et al.
SEMINARS IN REPRODUCTIVE MEDICINE (2007)
Dual signaling is differentially activated by different active states of the metabotropic glutamate receptor 1α
M Tateyama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
P Dorr et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Localized RhoA activation as a requirement for the induction of membrane ruffling
K Kurokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Essential role for the second extracellular loop in C5a receptor activation
JM Klco et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Tocolytic effect of a Rho-kinase inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery
M Tahara et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2005)
Design, synthesis, and application of azabicyclo[XYO]alkanone amino acids as constrained dipeptide surrogates and peptide mimics
J Cluzeau et al.
BIOPOLYMERS (2005)
Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis
GA Block et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors
A Lanzafame et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice
L Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
G-protein-coupled receptor allosterism: the promise and the problem(s)
A Christopoulos et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
Allergic sensitization enhances the contribution of Rho-kinase to airway smooth muscle contraction
D Schaafsma et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
The role of prostaglandins in the initiation of parturition
DM Olson
BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY (2003)
Myometrial activation and preterm labour: Evidence supporting a role for the prostaglandin F receptor - A review
DM Olson et al.
PLACENTA (2003)
Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F2α-induced contraction of rabbit aortae
K Ito et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
THG113: A novel selective FP antagonist that delays preterm labor
KG Peri et al.
SEMINARS IN PERINATOLOGY (2002)
Models and methods for studying insurmountable antagonism
G Vauquelin et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2002)
Activation of Rac and Cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells
RE Itoh et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
G protein-coupled receptor allosterism and complexing
A Christopoulos et al.
PHARMACOLOGICAL REVIEWS (2002)
Oxytocin antagonists: clinical and scientific considerations
S Thornton et al.
EXPERIMENTAL PHYSIOLOGY (2001)
Induction of c-fos and c-jun messenger ribonucleic acid expression by prostaglandin F2α is mediated by a protein kinase C-dependent extracellular signal-regulated kinase mitogen-activated protein kinase pathway in bovine luteal cells
DB Chen et al.
ENDOCRINOLOGY (2001)