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Sebastien Roger et al.
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The P2X7 receptor as a therapeutic target
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The P2X7 carboxyl tail is a regulatory module of P2X7 receptor channel activity
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Facilitation of P2X7 receptor currents and membrane blebbing via constitutive and dynamic calmodulin binding
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Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders
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A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis
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Amino acid residues in the P2X(7) receptor that mediate differential sensitivity to ATP and BzATP
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Physiology and pathophysiology of purinergic neurotransmission
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Characterization of a selective and potent antagonist of human P2X7 receptors, AZ11645373
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Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation
Isabella Derler et al.
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Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor
Pablo Pelegrin et al.
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Identification of Thr283 as a key determinant of P2X7 receptor function
M. T. Young et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
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Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists
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Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder
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The P2X7 receptor:: A key player in IL-1 processing and release
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A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages
AN Shemon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X7 receptors
LH Jiang et al.
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Pseudoapoptosis induced by brief activation of ATP-gated P2X7 receptors
AB Mackenzie et al.
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Multiple roles of calmodulin and other Ca2+-binding proteins in the functional regulation of TRP channels
MX Zhu
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Protein-protein interaction and functionTRPC channels
K Kiselyov et al.
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Functional expression of P2X7 receptors in non-neuronal cells of rat dorsal root ganglia
XF Zhang et al.
BRAIN RESEARCH (2005)
A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes
G Cabrini et al.
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Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth
E Adinolfi et al.
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Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide-induced cytokine production
LC Denlinger et al.
JOURNAL OF IMMUNOLOGY (2005)
Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
IP Chessell et al.
PAIN (2005)
Small conductance Ca2+-activated K+ channels and calmodulin
J Maylie et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Reanalysis of P2X7 receptor expression in rodent brain
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P2X7 receptor polymorphism impairs extracellular adenosine 5′-triphosphate-induced interleukin-18 release from human monocytes
R Sluyter et al.
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Novel P2X7 receptor antagonists
L Alcaraz et al.
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A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria
BM Saunders et al.
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Mutation of a dibasic amino acid motif within the C terminus of the P2X7 receptor results in trafficking defects and impaired function
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P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1β release
PA Verhoef et al.
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P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region
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Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia
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Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus
HL Wilson et al.
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Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response
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A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia:: a molecular study
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Proteomic and functional evidence for a P2X7 receptor signalling complex
M Kim et al.
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Apparent species differences in the kinetic properties of P2X7 receptors
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