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Nita H. Salzman et al.
NATURE IMMUNOLOGY (2010)
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Anionic Amino Acids near the Pro-α-defensin N Terminus Mediate Inhibition of Bactericidal Activity in Mouse Pro-cryptdin-4
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Impaired luminal processing of human defensin-5 in Crohn's disease - Persistence in a complex with chymotrypsinogen and trypsin
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Mechanisms of α-Defensin Bactericidal Action: Comparative Membrane Disruption by Cryptdin-4 and Its Disulfide-Null Analogue
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Jenny Karlsson et al.
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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
Arthur Kaser et al.
CELL (2008)
Multi-layered regulation of intestinal antimicrobial defense
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CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
The conserved salt bridge in human α-defensin 5 is required for its precursor processing and proteolytic stability
Mohsen Rajabi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
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Karishma Kamdar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Combination of ellipsometry, laser scanning microscopy and Z-scan fluorescence correlation spectroscopy elucidating interaction of cryptdin-4 with supported phospholipid bilayers
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JOURNAL OF PEPTIDE SCIENCE (2008)
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
Ken Cadwell et al.
NATURE (2008)
Resistin-like molecule β (RELMβ/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis
Sean L. Barnes et al.
JOURNAL OF IMMUNOLOGY (2007)
Impact of pro segments on the folding and function of human neutrophil α-defensins
Zhibin Wu et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Characterization of α-defensins plasma levels in Macaca fascicularis and correlations with virological parameters during SHIV89.6Pcy11 experimental infection
Silvia Baroncelli et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2007)
A pocket guide to explorations of the defensin field
Michael E. Selsted
CURRENT PHARMACEUTICAL DESIGN (2007)
Multispecific myeloid defensins
Robert I. Lehrer
CURRENT OPINION IN HEMATOLOGY (2007)
Matrix metalloproteinase-7 activation of mouse Paneth cell pro-α-defensins -: SER43↓ILE44 proteolysis enables membrane-disruptive activity
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mammalian defensins in the antimicrobial immune response
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NATURE IMMUNOLOGY (2005)
Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc mice
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AMERICAN JOURNAL OF PATHOLOGY (2005)
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CURRENT PROTEIN & PEPTIDE SCIENCE (2005)
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Increased diversity of intestinal antimicrobial peptides by covalent dimer formation
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NATURE IMMUNOLOGY (2004)
Rapid evolution and diversification of mammalian α-defensins as revealed by comparative analysis of rodent and primate genes
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PHYSIOLOGICAL GENOMICS (2004)
Functional analysis of the α-defensin disulfide array in mouse cryptdin-4
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice
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AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Antimicrobial peptides in animals and their role in host defences
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INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2003)
Interactions of mouse paneth cell α-defensins and α-defensin precursors with membranes
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Plicatamide, an antimicrobial octapeptide from Styela plicata Hemocytes
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis
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GASTROENTEROLOGY (2003)
Structural determinants of procryptdin recognition and cleavage by matrix metalloproteinase-7
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Quantitative interactions between cryptdin-4 amino terminal variants and membranes
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PEPTIDES (2003)
Paneth cell trypsin is the processing enzyme for human defensin-5
D Ghosh et al.
NATURE IMMUNOLOGY (2002)
Potassium release, a useful tool for studying antimicrobial peptides
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JOURNAL OF MICROBIOLOGICAL METHODS (2002)
Activation of Paneth cell α-defensins in mouse small intestine
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Homodimeric θ-defensins from Rhesus macaque leukocytes -: Isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The multifaceted Paneth cell
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CELLULAR AND MOLECULAR LIFE SCIENCES (2002)
Germ-free and colonized mice generate the same products from enteric prodefensins
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Characterization of luminal paneth cell α-defensins in mouse small intestine -: Attenuated antimicrobial activities of peptides with truncated amino termini
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)