相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cancer systems biology: a network modeling perspective
Pamela K. Kreeger et al.
CARCINOGENESIS (2010)
Impact of Feedback Phosphorylation and Raf Heterodimerization on Normal and Mutant B-Raf Signaling
Daniel A. Ritt et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
Poulikos I. Poulikakos et al.
NATURE (2010)
Negative and Positive Regulation of MAPK Phosphatase 3 Controls Platelet-derived Growth Factor-induced Erk Activation
Aleksandra Jurek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway
Sung-Young Shin et al.
JOURNAL OF CELL SCIENCE (2009)
C-Raf Inhibits MAPK Activation and Transformation by B-RafV600E
Florian A. Karreth et al.
MOLECULAR CELL (2009)
Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor
Harish Shankaran et al.
MOLECULAR SYSTEMS BIOLOGY (2009)
PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk
Chun-Chao Wang et al.
MOLECULAR SYSTEMS BIOLOGY (2009)
Why We Need Quantitative Dynamic Models
Ravi Iyengar
SCIENCE SIGNALING (2009)
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
Jeffrey A. Engelman
NATURE REVIEWS CANCER (2009)
Design principles of biochemical oscillators
Bela Novak et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Feedback loops shape cellular signals in space and time
Onn Brandman et al.
SCIENCE (2008)
Robust, tunable biological oscillations from interlinked positive and negative feedback loops
Tony Yu-Chen Tsai et al.
SCIENCE (2008)
Dose-to-Duration Encoding and Signaling beyond Saturation in Intracellular Signaling Networks
Marcelo Behar et al.
PLOS COMPUTATIONAL BIOLOGY (2008)
Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses
Marc R. Birtwistle et al.
MOLECULAR SYSTEMS BIOLOGY (2007)
Bistability and oscillations in the Huang-Ferrell model of MAPK signaling
Liang Qiao et al.
PLOS COMPUTATIONAL BIOLOGY (2007)
Regulation of gene transcription by mitogen-activated protein kinase signaling pathways
Alan J. Whitmarsh
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways
Marcelo Behar et al.
BIOPHYSICAL JOURNAL (2007)
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
P. J. Roberts et al.
ONCOGENE (2007)
Integrating signals from RTKs to ERK/MAPK
M. M. McKay et al.
ONCOGENE (2007)
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
S. Meloche et al.
ONCOGENE (2007)
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
D. M. Owens et al.
ONCOGENE (2007)
Role of mitogen-activated protein kinase kinase kinases in signal integration
B. D. Cuevas et al.
ONCOGENE (2007)
MAP kinase signalling pathways in cancer
A. S. Dhillon et al.
ONCOGENE (2007)
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
Silvia D. M. Santos et al.
NATURE CELL BIOLOGY (2007)
Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops
Anatoly Kiyatkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mechanisms of gradient sensing and chemotaxis - Conserved pathways, diverse regulation
Ian C. Schneider et al.
CELL CYCLE (2006)
Regulation and role of Raf-1/B-Raf heterodimerization
LK Rushworth et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Quantitative model of Ras-phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly
H Kaur et al.
BIOCHEMICAL JOURNAL (2006)
Quantitative modeling in cell biology: What is it good for?
Alex Mogilner et al.
DEVELOPMENTAL CELL (2006)
Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts
IC Schneider et al.
JOURNAL OF CELL BIOLOGY (2005)
Signaling interplay in Ras superfamily function
N Mitin et al.
CURRENT BIOLOGY (2005)
When kinases meet mathematics: the systems biology of MAPK signalling
W Kolch et al.
FEBS LETTERS (2005)
Regulation of raf-1 by direct feedback phosphorylation
MK Dougherty et al.
MOLECULAR CELL (2005)
Spatial analysis of 3 ' phosphoinositide signaling in living fibroblasts: II. Parameter estimates for individual cells from experiments
IC Schneider et al.
BIOPHYSICAL JOURNAL (2004)
Kinetic analysis of platelet-derived growth factor receptor/phosphoinositide 3-kinase/Akt signaling in fibroblasts
CS Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
US Bhalla et al.
SCIENCE (2002)
Models of eukaryotic gradient sensing: Application to chemotaxis of amoebae and neutrophils
A Levchenko et al.
BIOPHYSICAL JOURNAL (2002)
Robust perfect adaptation in bacterial chemotaxis through integral feedback control
TM Yi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
BN Kholodenko
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)