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Delphine Milhas et al.
FEBS LETTERS (2010)
Roles and regulation of secretory and lysosomal acid sphingomyelinase
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CELLULAR SIGNALLING (2009)
Acid sphingomyelinase activity triggers microparticle release from glial cells
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Sustained Receptor Stimulation Leads to Sequestration of Recycling Endosomes in a Classical Protein Kinase C- and Phospholipase D-dependent Manner
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Involvement of Acid β-Glucosidase 1 in the Salvage Pathway of Ceramide Formation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Acid β-Glucosidase 1 Counteracts p38δ-dependent Induction of Interleukin-6 POSSIBLE ROLE FOR CERAMIDE AS AN ANTI-INFLAMMATORY LIPID
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes
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NATURE IMMUNOLOGY (2009)
Single proteins might have dual but related functions in intracellular and extracellular microenvironments
Derek C. Radisky et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression
Cecilia M. Devlin et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)
A novel role for protein kinase C delta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury
Youssef H. Zeidan et al.
FASEB JOURNAL (2008)
The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases
Eric L. Smith et al.
FASEB JOURNAL (2008)
Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway
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JOURNAL OF CELL BIOLOGY (2008)
Characterization of common SMPD1 mutations causing types A and B Niemann-Pick disease and generation of mutation-specific mouse models
Iwan Jones et al.
MOLECULAR GENETICS AND METABOLISM (2008)
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Carboxyl-terminal disulfide bond of acid sphingomyelinase is critical for its secretion and enzymatic function
Ching Yin Lee et al.
BIOCHEMISTRY (2007)
Constitutive acid sphingomyelinase enhances early and late macrophage killing of Salmonella enterica serovar typhimurium
Bruce D. McCollister et al.
INFECTION AND IMMUNITY (2007)
The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease
E. H. Schuchman
JOURNAL OF INHERITED METABOLIC DISEASE (2007)
Activation of acid sphingomyelinase by protein kinase Cδ-mediated phosphorylation
Youssef H. Zeidan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Secretory sphingomyelinase is upregulated in chronic heart failure: a second messenger system of immune activation relates to body composition, muscular functional capacity, and peripheral blood flow
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EUROPEAN HEART JOURNAL (2007)
Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
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METHODS (2006)
Increased sphingomyelin content impairs HDL biogenesis and maturation in human Niemann-Pick disease type B
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JOURNAL OF LIPID RESEARCH (2006)
Physiological and pathophysiological aspects of ceramide
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AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis
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FASEB JOURNAL (2005)
Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment - Implications for endothelial apoptosis
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CANCER BIOLOGY & THERAPY (2005)
A model of the acid sphingomyelinase phosphoesterase domain based on its remote structural homolog purple acid phosphatase
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PROTEIN SCIENCE (2004)
Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine
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FEBS LETTERS (2004)
Acid and neutral sphingomyelinases: roles and mechanisms of regulation
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BIOCHEMISTRY AND CELL BIOLOGY (2004)
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NATURE REVIEWS CANCER (2004)
Sphingolipids in inflammation: Roles and implications
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CURRENT MOLECULAR MEDICINE (2004)
Sphingomyelinases:: enzymology and membrane activity
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FEBS LETTERS (2002)
Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Elevated sphingomyelinase and hypercytokinemia in hemophagocytic lymphohistiocytosis
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JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2002)
CD95 signaling via ceramide-rich membrane rafts
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Natural ceramide reverses Fas resistance of acid sphingomyelinase-/- hepatocytes
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Sphingomyelinase converts lipoproteins from apolipoprotein E knockout mice into potent inducers of macrophage foam cell formation
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ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
Detection sf abasic sites and oxidative DNA base damage using an ELISA-like assay
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METHODS (2000)
Creation of a mouse model for non-neurological (type B) Niemann-Pick disease by stable, low level expression of lysosomal sphingomyelinase in the absence of secretory sphingomyelinase: relationship between brain intra-lysosomal enzyme activity and central nervous system function
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HUMAN MOLECULAR GENETICS (2000)
Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo:: A possible link between inflammatory cytokines and atherogenesis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Characterization of sphingomyelinase activity released by thrombin-stimulated platelets
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MOLECULAR AND CELLULAR BIOCHEMISTRY (2000)