相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
Rui-Hong Wang et al.
CANCER CELL (2008)
SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity
Swami R. Narala et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth
Ron Firestein et al.
PLOS ONE (2008)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1
Sharon Wong et al.
BIOCHEMICAL JOURNAL (2007)
Sirtuins: critical regulators at the crossroads between cancer and aging
L. R. Saunders et al.
ONCOGENE (2007)
SIRT1 is significantly elevated in mouse and human prostate cancer
Derek M. Huffman et al.
CANCER RESEARCH (2007)
SIRT1 regulates the function of the nijmegen breakage syndrome protein
Zhigang Yuan et al.
MOLECULAR CELL (2007)
Strong expression of a longevity-related protein, SIRT1, in Bowen's disease
Yasutoshi Hida et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2007)
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
Kotb Abdelmohsen et al.
MOLECULAR CELL (2007)
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
Marie Lagouge et al.
CELL (2006)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Hormonal control of androgen receptor function through SIRT1
Maofu Fu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage
Chuangui Wang et al.
NATURE CELL BIOLOGY (2006)
Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes
B Heltweg et al.
CANCER RESEARCH (2006)
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells
L Bordone et al.
PLOS BIOLOGY (2006)
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
JM Solomon et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival
J Ford et al.
CANCER RESEARCH (2005)
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
WY Chen et al.
CELL (2005)
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
KA Moynihan et al.
CELL METABOLISM (2005)
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
KF Chua et al.
CELL METABOLISM (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
Mammalian SIRT1 represses forkhead transcription factors
MC Motta et al.
CELL (2004)
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen et al.
SCIENCE (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
F Yeung et al.
EMBO JOURNAL (2004)
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
HL Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Negative control of p53 by Sir2α promotes cell survival under stress
JY Luo et al.
CELL (2001)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
HA Tissenbaum et al.
NATURE (2001)
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
SJ Lin et al.
SCIENCE (2000)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)