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L Levy et al.
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ND Hendrix et al.
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J Zavadil et al.
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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
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K Basso et al.
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SU Han et al.
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J Lapointe et al.
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T Cardozo et al.
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FJ Nicolás et al.
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Loss of Smad3 in acute T-cell lymphoblastic leukemia
LA Wolfraim et al.
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Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy
YP Yu et al.
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Cyclin-dependent kinases regulate the antiproliferative function of Smads
I Matsuura et al.
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Gene expression patterns that characterize advanced stage serous ovarian cancers
JM Lancaster et al.
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Mechanisms of TGF-β signaling from cell membrane to the nucleus
YG Shi et al.
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Localization of activin and inhibin subunits, receptors and SMADs in the mouse mammary gland
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Stoichiometry of active Smad-transcription factor complexes on DNA
GJ Inman et al.
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Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis:: dissection of Ras signaling pathways
E Janda et al.
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R Derynck et al.
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TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest
C Petritsch et al.
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Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus
CE Pierreux et al.
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AA Alizadeh et al.
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