4.7 Article

Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 59, 期 8, 页码 4375-4378

出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00553-15

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资金

  1. Cleveland Department of Veterans Affairs (VA)
  2. Geriatric Research Education and Clinical Center VISN [10]
  3. VA Merit Review Program [1I01BX001974]
  4. National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) [R01AI063517, R01AI10056]
  5. Antibiotic Resistance Leadership Group (from NIH) [UM1AI104681]
  6. Clinical and Translational Science Collaborative of Cleveland (from the National Center for Advancing Translational Sciences) [UL1TR000439]

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Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite antibiotic treatment, she experienced spontaneous prolonged rupture of membranes, with eventual delivery of a healthy infant. This report demonstrates the challenge that CRE may pose to the effective treatment of common infections in obstetric patients, with potentially harmful consequences to maternal and neonatal health.

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