相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma
Meike Vogler et al.
CANCER RESEARCH (2009)
Development of novel drugs targeting inhibitors of apoptosis
John A. Flygare et al.
FUTURE ONCOLOGY (2009)
Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim
Thomas Kaufmann et al.
IMMUNITY (2009)
The Many Roles of FAS Receptor Signaling in the Immune System
Andreas Strasser et al.
IMMUNITY (2009)
XIAP discriminates between type I and type II FAS-induced apoptosis
Philipp J. Jost et al.
NATURE (2009)
Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5
C. Adams et al.
CELL DEATH AND DIFFERENTIATION (2008)
Cooperation of the Agonistic DR5 Antibody Apomab with Chemotherapy to Inhibit Orthotopic Lung Tumor Growth and Improve Survival
Hongkui Jin et al.
CLINICAL CANCER RESEARCH (2008)
Targeting the extrinsic apoptosis pathway in cancer
Avi Ashkenazi
CYTOKINE & GROWTH FACTOR REVIEWS (2008)
Switch from Type II to I Fas/CD95 Death Signaling on In Vitro Culturing of Primary Hepatocytes
Dorothee Walter et al.
HEPATOLOGY (2008)
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation
Eugene Varfolomeev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
Mathieu J. M. Bertrand et al.
MOLECULAR CELL (2008)
Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
Avi Ashkenazi
NATURE REVIEWS DRUG DISCOVERY (2008)
IAP-targeted therapies for cancer
E. C. LaCasse et al.
ONCOGENE (2008)
A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-α signaling
Alex Gaither et al.
CANCER RESEARCH (2007)
IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis
Eugene Varfolomeev et al.
CELL (2007)
IAP antagonists target cIAP1 to induce TNFα- dependent apoptosis
James E. Vince et al.
CELL (2007)
Autocrine TNFα signaling renders human cancer cells susceptible to smac-mimetic-induced apoptosis
Sean L. Petersen et al.
CANCER CELL (2007)
The inhibitor of apoptosis proteins as therapeutic targets in cancer
Domagoj Vucic et al.
CLINICAL CANCER RESEARCH (2007)
The BH3-only protein bid is dispensable for DNA darnage- and replicative stress-induced apoptosis or cell-cycle arrest
Thomas Kaufmann et al.
CELL (2007)
The inhibitors of apoptosis (IAPs) as cancer targets
Allison M. Hunter et al.
APOPTOSIS (2007)
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
Brendan P. Eckelman et al.
EMBO REPORTS (2006)
A common allosteric site and mechanism in caspases
Justin M. Scheer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs
Kerry Zobel et al.
ACS CHEMICAL BIOLOGY (2006)
Promoting apoptosis as a strategy for cancer drug discovery
SW Fesik
NATURE REVIEWS CANCER (2005)
A role for proapoptotic BID in the DNA-damage response
SS Zinkel et al.
CELL (2005)
Malonate-assisted purification of human caspases
JM Scheer et al.
PROTEIN EXPRESSION AND PURIFICATION (2005)
Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies
GS Salvesen et al.
ONCOGENE (2004)
Caspase activation, inhibition, and reactivation: A mechanistic view
YG Shi
PROTEIN SCIENCE (2004)
Alterations in the apoptotic machinery and their potential role in anticancer drug resistance
SH Kaufmann et al.
ONCOGENE (2003)
A unified model for apical caspase activation
KM Boatright et al.
MOLECULAR CELL (2003)
Mechanism of XIAP-mediated inhibition of caspase-9
EN Shiozaki et al.
MOLECULAR CELL (2003)
The BCL2 family: Regulators of the cellular life-or-death switch
S Cory et al.
NATURE REVIEWS CANCER (2002)
IAP proteins: Blocking the road to death's door
GS Salvesen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
CY Du et al.
CELL (2000)
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
AM Verhagen et al.
CELL (2000)
分享论文
