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PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase
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Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats
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Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1
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Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes
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TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function
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The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
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Identification of a proline-rich Akt substrate as a 14-3-3 binding partner
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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-Kinase/Akt pathway
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Identification of a conserved motif required for mTOR signaling
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