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The decorin sequence SYIRIADTNIT binds collagen type I
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Biglycan deficiency causes spontaneous aortic dissection and rupture in mice
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Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia
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Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and mammalian target of rapamycin
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On the origins of the extracellular matrix in vertebrates
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Decorin modulates fibrin assembly and structure
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Tsukushi cooperates with VG1 to induce primitive streak and Hensen's node formation in the chick embryo
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Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation
Daniela G. Seidler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans
Paul A. McEwan et al.
JOURNAL OF STRUCTURAL BIOLOGY (2006)
Extracellular proteoglycans modify TGF-β bio-availability attenuating its signaling during skeletal muscle differentiation
Rebeca Droguett et al.
MATRIX BIOLOGY (2006)
Tsukushi controls ectodermal patterning and neural crest specification in Xenopus by direct regulation of BMP4 and X-delta-1 activity
S Kuriyama et al.
DEVELOPMENT (2006)
Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis
JX Zhu et al.
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The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
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Decorin, a novel player in the insulin-like growth factor system
E Schönherr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway
M Moreno et al.
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Decorin prevents metastatic spreading of breast cancer
CC Reed et al.
ONCOGENE (2005)
Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene
C Bredrup et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family
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Biologically active decorin is a monomer in solution
S Goldoni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin
K Ohta et al.
DEVELOPMENTAL CELL (2004)
Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury
L Schaefer et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
PG Scott et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation
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FASEB JOURNAL (2004)
Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice
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A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mice deficient in small leucine-rich proteoglycans:: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases
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Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues
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JOURNAL OF BONE AND MINERAL RESEARCH (2002)
Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin
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ONCOGENE (2002)
The role of decorin in collagen fibrillogenesis and skin homeostasis
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Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction
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AMERICAN JOURNAL OF PATHOLOGY (2002)
Decorin-mediated signal transduction in endothelial cells -: Involvement of Akt/protein kinase B in up-regulation of p21WAF1/CIP1 but not p27KIP1
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Expression pattern and gene characterization of asporin -: A newly discovered member of the leucine-rich repeat protein family
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The complete form of X-linked congenital stationary night blindness is caused by mutations in a gene encoding a leucine-rich repeat protein
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NATURE GENETICS (2000)
Mutations in NYX, encoding the leucine-rich proteoglycan nyctalopin, cause X-linked complete congenital stationary night blindness
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NATURE GENETICS (2000)
Sustained down-regulation of the epidermal growth factor receptor by decorin -: A mechanism for controlling tumor growth in vivo
G Csordás et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Mutations in KERA, encoding keratocan, cause cornea plana
NS Pellegata et al.
NATURE GENETICS (2000)
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