期刊
JOURNAL OF BIOLOGICAL CHEMISTRY
卷 284, 期 18, 页码 11761-11765出版社
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/jbc.R800074200
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资金
- National Institutes of Health [GM058859]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM058859] Funding Source: NIH RePORTER
Despite having been identified first, their greater degree of complexity has resulted in our understanding of eukaryotic ribosomes lagging behind that of their bacterial and archaeal counterparts. A much more complicated biogenesis program results in ribosomes that are structurally, biochemically, and functionally more complex. However, recent advances in molecular genetics and structural biology are helping to reveal the intricacies of the eukaryotic ribosome and to address many longstanding questions regarding its many roles in the regulation of gene expression.
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