4.6 Review

Structure-based Ligand Design and the Promise Held for Antiprotozoan Drug Discovery

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Novel molecular targets for antimalarial drug development

Nitendra K. Sahu et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2008)

Review Pharmacology & Pharmacy

Fatty acid synthesis in protozoan parasites: Unusual pathways and novel drug targets

C. D. Goodman et al.

CURRENT PHARMACEUTICAL DESIGN (2008)

Review Medicine, Research & Experimental

Kinetoplastids: related protozoan pathogens, different diseases

Ken Stuart et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Chemistry, Medicinal

Natural products as leads to potential drugs: An old process or the new hope for drug discovery?

David J. Newman

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

Global trends in emerging infectious diseases

Kate E. Jones et al.

NATURE (2008)

Review Biochemistry & Molecular Biology

Network pharmacology: the next paradigm in drug discovery

Andrew L. Hopkins

NATURE CHEMICAL BIOLOGY (2008)

Article Multidisciplinary Sciences

Drug target identification using side-effect similarity

Monica Campillos et al.

SCIENCE (2008)

Review Pharmacology & Pharmacy

Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

M. P. Barrett et al.

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Review Parasitology

Target assessment for antiparasitic drug discovery

Julie A. Frearson et al.

TRENDS IN PARASITOLOGY (2007)

Review Biochemistry & Molecular Biology

The non-mevalonate pathway of isoprenoid precursor biosynthesis

William N. Hunter

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biotechnology & Applied Microbiology

Structure-based maximal affinity model predicts small-molecule druggability

Alan C. Cheng et al.

NATURE BIOTECHNOLOGY (2007)

Review Infectious Diseases

Cutaneous leishmaniasis

Richard Reithinger et al.

LANCET INFECTIOUS DISEASES (2007)

Review Plant Sciences

Natural products as sources of new drugs over the last 25 years

David J. Newman et al.

JOURNAL OF NATURAL PRODUCTS (2007)

Review Biochemistry & Molecular Biology

Computational approaches on angiotensin receptors and their ligands: Recent developments and results

Tiziano Tuccinardi et al.

CURRENT MEDICINAL CHEMISTRY (2007)

Review Biotechnology & Applied Microbiology

A decade of fragment-based drug design: strategic advances and lessons learned

Philip J. Hajduk et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Review Biochemistry & Molecular Biology

Drug discovery and development for neglected parasitic diseases

Adam R. Renslo et al.

NATURE CHEMICAL BIOLOGY (2006)

Review Genetics & Heredity

Switching trypanosome coats: what's in the wardrobe?

Jesse E. Taylor et al.

TRENDS IN GENETICS (2006)

Review Biotechnology & Applied Microbiology

Innovative lead discovery strategies for tropical diseases

Solomon Nwaka et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Biochemistry & Molecular Biology

Therapeutic intervention based on protein prenylation and associated modifications

Michael H. Gelb et al.

NATURE CHEMICAL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

A practical view of 'druggability'

Thomas H. Keller et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2006)

Review Chemistry, Medicinal

Drug targets for Plasmodium falciparum:: A post-genomic review/survey

I Yeh et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Can we rationally design promiscuous drugs?

AL Hopkins et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2006)

Review Microbiology

Drug resistance in leishmaniasis

SL Croft et al.

CLINICAL MICROBIOLOGY REVIEWS (2006)

Article Biochemistry & Molecular Biology

Protein kinases as drug targets in trypanosomes and Leishmania

C Naula et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)

Review Parasitology

Chemotherapy of trypanosomiases and leishmaniasis

SL Croft et al.

TRENDS IN PARASITOLOGY (2005)

Article Biotechnology & Applied Microbiology

Protozoan genomics for drug discovery

K Chaudhary et al.

NATURE BIOTECHNOLOGY (2005)

Review Pharmacology & Pharmacy

Keynote review: Structural biology and drug discovery

M Congreve et al.

DRUG DISCOVERY TODAY (2005)

Article Biotechnology & Applied Microbiology

Fragment-based lead discovery

DC Rees et al.

NATURE REVIEWS DRUG DISCOVERY (2004)

Article Multidisciplinary Sciences

Navigating chemical space for biology and medicine

C Lipinski et al.

NATURE (2004)

Article Multidisciplinary Sciences

Virtual screening of chemical libraries

BK Shoichet

NATURE (2004)

Review Chemistry, Medicinal

Fragment-based drug discovery

DA Erlanson et al.

JOURNAL OF MEDICINAL CHEMISTRY (2004)

Review Infectious Diseases

The global distribution and population at risk of malaria: past, present, and future

SI Hay et al.

LANCET INFECTIOUS DISEASES (2004)

Review Pharmacology & Pharmacy

Rediscovering the sweet spot in drug discovery

D Brown et al.

DRUG DISCOVERY TODAY (2003)

Review Biochemistry & Molecular Biology

The parasite-specific trypanothione metabolism of trypanosoma and leishmania

RL Krauth-Siegel et al.

BIOLOGICAL CHEMISTRY (2003)

Article Biotechnology & Applied Microbiology

The druggable genome

AL Hopkins et al.

NATURE REVIEWS DRUG DISCOVERY (2002)